Interactor 1: Q9N6D8 (Q9N6D8)
GH11591p (Transcription factor) (p53 tumor suppressor-like protein) (p53, isoform A) (p53, isoform C) (p53-like regulator of apoptosis and cell cycle)
Gene: p53

Interactor 2: SIRT1 (Q9VK34)
NAD-dependent histone deacetylase sirtuin-1 (EC 2.3.1.286) (Silent information regulator 2)
Gene: SIRT1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 19851477
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0008134 - transcription factor binding
GO:0008340 - determination of adult lifespan
GO:0046872 - metal ion binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 385
Dm

1 823
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024