HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: IFIH1 (Q9BYX4)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116)
Gene: IFIH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 20127681
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Helicase_C, DEAD~RIG-I_C, DEAD~RIG-I_C-RD, Helicase_C~Helicase_C, Helicase_C~ResIII, Helicase_C~RIG-I_C, Helicase_C~RIG-I_C-RD
Common GO terms GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 8 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 662
Hs

1 1025
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Sc
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024