Protein: MTCH1
Mitochondrial carrier homolog 1 (Presenilin-associated protein)

Gene: MTCH1
Organism: Homo sapiens
Interactions: 197
UniProt ID: Q9NZJ7

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0006915 - apoptotic process
GO:0009966 - regulation of signal transduction
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1452311

SCN3B
Sodium channel regulatory subunit beta-3

3

5

High-throughput

0.855

High

1350091

SPP2B
Signal peptide peptidase-like 2B

3

1

High-throughput

0.662

High

252639

TSN2
Tetraspanin-2

2

1

High-throughput

0.628

High

1293925

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

8

High-throughput

0.618

High

1382965

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

Small-scale

0.618

High

1453394

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

8

High-throughput

0.618

High

209128

CYB5B
Cytochrome b5 type B

2

2

High-throughput

0.611

High

635395

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

3

3

High-throughput

0.604

High

1366606

AKAP1
A-kinase anchor protein 1, mitochondrial

2

7

High-throughput

0.584

High

1365521

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

2

2

High-throughput

0.574

High

318068

TOM70
Mitochondrial import receptor subunit TOM70

2

13

High-throughput

0.571

High

326624

MFN2
Mitofusin-2

2

3

High-throughput

0.571

High

360139

NB5R3
NADH-cytochrome b5 reductase 3

2

4

High-throughput

0.571

High

988767

RAC1
Ras-related C3 botulinum toxin substrate 1

2

13

High-throughput

0.571

High

1242131

MTFR2
Mitochondrial fission regulator 2

2

5

High-throughput

0.571

High

1258010

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

2

6

High-throughput

0.571

High

1309744

MFN1
Mitofusin-1

2

3

High-throughput

0.571

High

1332673

MIGA1
Mitoguardin 1

2

3

High-throughput

0.571

High

1403815

RMD3
Regulator of microtubule dynamics protein 3

2

2

High-throughput

0.571

High

1429142

MFF
Mitochondrial fission factor

2

1

High-throughput

0.571

High

1433698

TRABD
TraB domain-containing protein

2

1

High-throughput

0.571

High

1450500

DJC11
DnaJ homolog subfamily C member 11

2

13

High-throughput

0.571

High

1453383

ARMX3
Armadillo repeat-containing X-linked protein 3

2

4

High-throughput

0.571

High

1453395

TDRKH
Tudor and KH domain-containing protein

2

12

High-throughput

0.571

High

1339469

TOIP2
Torsin-1A-interacting protein 2

2

4

High-throughput

0.552

High

1128848

NBR1
Next to BRCA1 gene 1 protein

2

0

High-throughput

0.547

High

1310477

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1399399

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

7

High-throughput

0.536

High

1446590

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

1

High-throughput

0.536

High

1433278

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

3

High-throughput

0.533

High

1386395

FAF2
FAS-associated factor 2

2

10

High-throughput

0.521

High

486632

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

891335

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.508

High

508738

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.501

High

771256

APJ
Apelin receptor

1

15

High-throughput

0.494

High

376648

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

5

High-throughput

0.489

High

469562

SYPH
Synaptophysin

1

3

High-throughput

0.489

High

1089274

TRI26
Tripartite motif-containing protein 26

1

7

High-throughput

0.489

High

1254087

LRC55
Leucine-rich repeat-containing protein 55

1

6

High-throughput

0.489

High

1308999

S22A9
Organic anion transporter 7

1

12

High-throughput

0.489

High

1363153

CLC2B
C-type lectin domain family 2 member B

1

9

High-throughput

0.489

High

1451402

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

3

High-throughput

0.489

High

411088

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

8

High-throughput

0.481

High

106755

APRIO
Alternative prion protein

1

5

High-throughput

0.479

High

135722

DNM1L
Dynamin-1-like protein

1

3

High-throughput

0.479

High

181450

PGRC2
Membrane-associated progesterone receptor component 2

1

2

High-throughput

0.479

High

192335

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

239400

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

3

High-throughput

0.479

High

259148

DNJA2
DnaJ homolog subfamily A member 2

1

8

High-throughput

0.479

High

269069

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

3

High-throughput

0.479

High

275408

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

1

High-throughput

0.479

High

278986

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.479

High

281108

TACC1
Transforming acidic coiled-coil-containing protein 1

1

8

High-throughput

0.479

High

281684

MTX2
Metaxin-2

1

4

High-throughput

0.479

High

320104

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

343491

SNP29
Synaptosomal-associated protein 29

1

1

High-throughput

0.479

High

354418

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

7

High-throughput

0.479

High

541722

FGFR1
Fibroblast growth factor receptor 1

1

7

Small-scale

0.479

High

568861

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

4

High-throughput

0.479

High

611390

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.479

High

621539

HXK1
Hexokinase-1

1

4

High-throughput

0.479

High

701928

ABCD3
ATP-binding cassette sub-family D member 3

1

5

High-throughput

0.479

High

732859

GLPK
Glycerol kinase

1

1

High-throughput

0.479

High

896323

PEX5
Peroxisomal targeting signal 1 receptor

1

3

High-throughput

0.479

High

901626

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

914132

HXK2
Hexokinase-2

1

4

High-throughput

0.479

High

1036258

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

3

High-throughput

0.479

High

1038713

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

7

High-throughput

0.479

High

1051974

KPCD
Protein kinase C delta type

1

16

High-throughput

0.479

High

1063195

GOGA3
Golgin subfamily A member 3

1

6

High-throughput

0.479

High

1092099

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

3

High-throughput

0.479

High

1125706

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

6

High-throughput

0.479

High

1147754

MTFR1
Mitochondrial fission regulator 1

1

5

High-throughput

0.479

High

1164604

MIC60
MICOS complex subunit MIC60

1

2

High-throughput

0.479

High

1187386

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

4

High-throughput

0.479

High

1204962

MTX3
Metaxin-3

1

4

High-throughput

0.479

High

1214821

ATD3B
ATPase family AAA domain-containing protein 3B

1

13

High-throughput

0.479

High

1215641

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

1

High-throughput

0.479

High

1216567

VP13D
Intermembrane lipid transfer protein VPS13D

1

4

High-throughput

0.479

High

1246029

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

2

High-throughput

0.479

High

1247529

POTEE
POTE ankyrin domain family member E

1

2

High-throughput

0.479

High

1259168

LARP4
La-related protein 4

1

5

High-throughput

0.479

High

1278132

MAVS
Mitochondrial antiviral-signaling protein

1

7

High-throughput

0.479

High

1312290

MIRO2
Mitochondrial Rho GTPase 2

1

16

High-throughput

0.479

High

1324254

ARM10
Armadillo repeat-containing protein 10

1

4

High-throughput

0.479

High

1392685

MYO19
Unconventional myosin-XIX

1

1

High-throughput

0.479

High

1401529

VP13A
Intermembrane lipid transfer protein VPS13A

1

4

High-throughput

0.479

High

1405889

DNJC7
DnaJ homolog subfamily C member 7

1

7

High-throughput

0.479

High

1410683

APOL2
Apolipoprotein L2

1

1

High-throughput

0.479

High

1412703

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1416219

FUND2
FUN14 domain-containing protein 2

1

1

High-throughput

0.479

High

1416992

B2L13
Bcl-2-like protein 13

1

2

High-throughput

0.479

High

1420429

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

2

High-throughput

0.479

High

1429330

MFR1L
Mitochondrial fission regulator 1-like

1

5

High-throughput

0.479

High

1435380

EGLN3
Prolyl hydroxylase EGLN3

1

5

High-throughput

0.479

High

1447112

MID51
Mitochondrial dynamics protein MIEF1

1

2

High-throughput

0.479

High

1450453

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1450585

ATD3A
ATPase family AAA domain-containing protein 3A

1

15

High-throughput

0.479

High

1451161

ARGL1
Arginine and glutamate-rich protein 1

1

1

High-throughput

0.479

High

1451733

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

1451863

MIC19
MICOS complex subunit MIC19

1

2

High-throughput

0.479

High

1452977

CISD1
CDGSH iron-sulfur domain-containing protein 1

1

2

High-throughput

0.479

High

1453388

FBXL4
F-box/LRR-repeat protein 4

1

5

High-throughput

0.479

High

1453390

CHIP
E3 ubiquitin-protein ligase CHIP

1

10

High-throughput

0.479

High

1453393

TRAK1
Trafficking kinesin-binding protein 1

1

7

High-throughput

0.479

High

1453397

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

249527

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.458

High

275775

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

0

High-throughput

0.458

High

828461

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.458

High

888776

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

0

High-throughput

0.458

High

890065

PSN1
Presenilin-1

1

0

Small-scale

0.458

High

1214592

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1326537

TOM5
Mitochondrial import receptor subunit TOM5 homolog

1

0

High-throughput

0.458

High

1389846

SIM12
Small integral membrane protein 12

1

0

High-throughput

0.458

High

1413911

LMF2
Lipase maturation factor 2

1

0

High-throughput

0.458

High

134172

IPO5
Importin-5

1

2

High-throughput

0.445

High

219663

B2L11
Bcl-2-like protein 11

1

1

High-throughput

0.445

High

248957

GSDME
Gasdermin-E

1

2

High-throughput

0.445

High

251263

RNBP6
Ran-binding protein 6

1

2

High-throughput

0.445

High

989810

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

1

High-throughput

0.445

High

1131636

MFS10
Major facilitator superfamily domain-containing protein 10

1

8

High-throughput

0.445

High

1247715

SARM1
NAD(+) hydrolase SARM1

1

2

High-throughput

0.445

High

1272096

MIGA2
Mitoguardin 2

1

3

High-throughput

0.445

High

1331268

ARL10
ADP-ribosylation factor-like protein 10

1

3

High-throughput

0.445

High

1346810

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

2

High-throughput

0.445

High

1348077

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

2

High-throughput

0.445

High

1381403

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

8

High-throughput

0.445

High

1381809

MARC2
Mitochondrial amidoxime reducing component 2

1

2

High-throughput

0.445

High

1439251

GPAT1
Glycerol-3-phosphate acyltransferase 1, mitochondrial

1

1

High-throughput

0.445

High

1450026

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

1

High-throughput

0.445

High

1451780

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

1

High-throughput

0.445

High

1453387

FEM1B
Protein fem-1 homolog B

1

6

High-throughput

0.445

High

1453391

MAGD2
Melanoma-associated antigen D2

1

9

High-throughput

0.445

High

215355

TXNL1
Thioredoxin-like protein 1

1

5

High-throughput

0.437

High

231775

PEX1
Peroxisomal ATPase PEX1

1

5

High-throughput

0.437

High

294442

CD123
Translation initiation factor eIF2 assembly protein

1

7

High-throughput

0.437

High

377760

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

2

High-throughput

0.437

High

630651

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.437

High

648245

NDKB
Nucleoside diphosphate kinase B

1

3

High-throughput

0.437

High

725558

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

4

High-throughput

0.437

High

731654

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.437

High

895971

F10A1
Hsc70-interacting protein

1

12

High-throughput

0.437

High

905217

MECP2
Methyl-CpG-binding protein 2

1

7

High-throughput

0.437

High

906204

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

3

High-throughput

0.437

High

981372

RAB1A
Ras-related protein Rab-1A

1

1

High-throughput

0.437

High

1005185

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

1048296

KPCT
Protein kinase C theta type

1

16

High-throughput

0.437

High

1101318

SLAF1
Signaling lymphocytic activation molecule

1

5

High-throughput

0.437

High

1103668

PHLP
Phosducin-like protein

1

1

High-throughput

0.437

High

1153937

SMAD2
Mothers against decapentaplegic homolog 2

1

4

Small-scale

0.437

High

1177111

INF2
Inverted formin-2

1

3

High-throughput

0.437

High

1194630

DUS28
Dual specificity phosphatase 28

1

6

High-throughput

0.437

High

1210126

SNP47
Synaptosomal-associated protein 47

1

1

High-throughput

0.437

High

1228949

CRBG3
Very large A-kinase anchor protein

1

2

High-throughput

0.437

High

1249273

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1252998

BAKOR
Beclin 1-associated autophagy-related key regulator

1

4

High-throughput

0.437

High

1255861

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

1308601

NUDC3
NudC domain-containing protein 3

1

4

High-throughput

0.437

High

1336693

EHBP1
EH domain-binding protein 1

1

3

High-throughput

0.437

High

1353216

SMCR8
Guanine nucleotide exchange protein SMCR8

1

1

High-throughput

0.437

High

1357297

CHMP7
Charged multivesicular body protein 7

1

5

High-throughput

0.437

High

1357433

DEP1B
DEP domain-containing protein 1B

1

5

High-throughput

0.437

High

1365072

UBXN4
UBX domain-containing protein 4

1

10

High-throughput

0.437

High

1371744

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

Small-scale

0.437

High

1393773

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.437

High

1397500

CI072
Guanine nucleotide exchange factor C9orf72

1

7

High-throughput

0.437

High

1429376

SPRTN
DNA-dependent metalloprotease SPRTN

1

5

High-throughput

0.437

High

1437517

WDR41
WD repeat-containing protein 41

1

8

High-throughput

0.437

High

1437749

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

6

High-throughput

0.437

High

1448919

DUS22
Dual specificity protein phosphatase 22

1

6

High-throughput

0.437

High

1453382

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

5

High-throughput

0.437

High

1453384

MLX
Max-like protein X

1

11

High-throughput

0.437

High

1453385

CDC23
Cell division cycle protein 23 homolog

1

4

High-throughput

0.437

High

1453386

APC7
Anaphase-promoting complex subunit 7

1

4

High-throughput

0.437

High

1453389

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

High-throughput

0.437

High

1453396

SGT1
Protein SGT1 homolog

1

8

High-throughput

0.437

High

1453398

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.437

High

331604

KIF4A
Chromosome-associated kinesin KIF4A

1

0

High-throughput

0.426

High

1254199

MFSD6
Major facilitator superfamily domain-containing protein 6

1

0

High-throughput

0.426

High

1347941

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.426

High

1453392

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.426

High

679408

DNJB2
DnaJ homolog subfamily B member 2

1

4

High-throughput

0.407

High

1113007

CUL2
Cullin-2

1

12

High-throughput

0.407

High

1134180

NTCP
Hepatic sodium/bile acid cotransporter

1

2

High-throughput

0.407

High

1227593

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.407

High

1349343

TBC15
TBC1 domain family member 15

1

3

High-throughput

0.407

High

1356678

S22AH
Solute carrier family 22 member 17

1

12

High-throughput

0.407

High

1365135

SL9A6
Sodium/hydrogen exchanger 6

1

1

High-throughput

0.407

High

1392486

TECT2
Tectonic-2

2

0

High-throughput

0.328

High

1409901

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.279

Low

1446617

RIC8A
Chaperone Ric-8A

1

0

High-throughput

0.279

Low

1147296

ELOB
Elongin-B

1

0

High-throughput

0.249

Low

1330956

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.249

Low

1437962

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

1211082

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low

1389609

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

1421070

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025