Interactor 1: ISK5 (Q9NQ38)
Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665]
Gene: SPINK5

Interactor 2: KLK5 (Q9Y337)
Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme)
Gene: KLK5

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 22588119, 10419450
Identification Methods protein array, surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Kazal_1~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0097209 - epidermal lamellar body
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1064
Hs

1 293
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024