HitPredict

Interactor 1: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Interactor 2: WDR3 (Q9UNX4)
WD repeat-containing protein 3
Gene: WDR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 619 Hs			1 943
+	Hs
		818610 SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69		WDR3_HUMAN (1-943): 0: 650: 100.00
+	Hs
		1281409 TF7L2_HUMAN (1-619): 4e-84: 277: 100.00		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		881823 SOX10_HUMAN (312-612): 6.86e-48: 176: 17.10		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		903450 CIC_HUMAN (43-578): 1.85e-33: 139: 15.01		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		903155 SRY_HUMAN (306-507): 4.03e-31: 122: 17.73		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		903169 SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		817868 SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69		WDR5_HUMAN (663-860): 4.99e-35: 138: 10.89
+	Hs
		996881 SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89		TBL1R_HUMAN (3-138): 9.77e-27: 117: 17.93
+	Hs
		818441 SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69		TBL1R_HUMAN (3-138): 9.77e-27: 117: 17.93
+	Mm
		1142008 Q60I23_MOUSE (318-613): 2.23e-26: 111: 14.47		TBL1R_MOUSE (3-138): 8.23e-27: 117: 17.93
+	Hs
		254063 SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69		WDR1_HUMAN (603-905): 7.64e-26: 115: 10.00
+	Hs
		996813 SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		1281404 HM20A_HUMAN (250-461): 2.79e-27: 115: 14.15		FBXW7_HUMAN (35-172): 1.4e-24: 112: 17.69
+	Hs
		818286 SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69		UTP15_HUMAN (218-514): 4.75e-22: 103: 12.67
+	Ce
		1089274 SOX2_CAEEL (315-526): 8.43e-34: 132: 17.21		WDR51_CAEEL (1-92): 2.51e-15: 80.7: 15.46
+	Hs
		817979 SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69		TBL3_HUMAN (4-93): 1.78e-17: 89.6: 13.33
+	Hs
		996886 SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89		SKI8_HUMAN (486-703): 8.04e-10: 63.2: 25.56
+	Hs
		996930 SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89		NLE1_HUMAN (748-843): 7.27e-09: 61.4: 4.12