Protein: RM39
Large ribosomal subunit protein mL39 (39S ribosomal protein L39, mitochondrial) (L39mt) (MRP-L39) (39S ribosomal protein L5, mitochondrial) (L5mt) (MRP-L5)

Gene: RM39, MRPL39
Organism: Homo sapiens
Interactions: 209
UniProt ID: Q9NYK5

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005761 - mitochondrial ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1123458

ICT1
Large ribosomal subunit protein mL62

5

1

High-throughput

0.718

High

1418323

RM01
Large ribosomal subunit protein uL1m

4

2

High-throughput

0.699

High

351020

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

4

1

High-throughput

0.694

High

477877

RM03
Large ribosomal subunit protein uL3m

4

3

High-throughput

0.694

High

882394

RM19
Large ribosomal subunit protein bL19m

4

2

High-throughput

0.694

High

1387982

RM38
Large ribosomal subunit protein mL38

4

1

High-throughput

0.694

High

1418155

RM13
Large ribosomal subunit protein uL13m

4

1

High-throughput

0.694

High

1437112

RM44
Large ribosomal subunit protein mL44

4

1

High-throughput

0.694

High

1448962

RM17
Large ribosomal subunit protein bL17m

4

1

High-throughput

0.694

High

1328315

RM50
Large ribosomal subunit protein mL50

5

0

High-throughput

0.688

High

76056

B4DEF8
Large ribosomal subunit protein mL45

4

1

High-throughput

0.686

High

1452676

RM42
Large ribosomal subunit protein mL42

5

0

High-throughput

0.682

High

1281356

RM10
Large ribosomal subunit protein uL10m

3

1

High-throughput

0.667

High

1312784

RM41
Large ribosomal subunit protein mL41

3

1

High-throughput

0.667

High

1386039

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

3

1

High-throughput

0.667

High

1446053

RT30
Large ribosomal subunit protein mL65

3

2

High-throughput

0.667

High

1451508

RM22
Large ribosomal subunit protein uL22m

3

1

High-throughput

0.667

High

1451677

RM16
Large ribosomal subunit protein uL16m

3

1

High-throughput

0.667

High

1452671

SYYM
Tyrosine--tRNA ligase, mitochondrial

3

1

High-throughput

0.667

High

1094143

RM28
Large ribosomal subunit protein bL28m

4

0

High-throughput

0.664

High

1104139

RM49
Large ribosomal subunit protein mL49

4

0

High-throughput

0.664

High

1388434

MTEF3
Transcription termination factor 3, mitochondrial

4

0

High-throughput

0.664

High

1418268

RM04
Large ribosomal subunit protein uL4m

4

0

High-throughput

0.664

High

1430524

RM18
Large ribosomal subunit protein uL18m

4

0

High-throughput

0.664

High

1446264

NGRN
Neugrin

4

0

High-throughput

0.664

High

1450793

RT18A
Large ribosomal subunit protein mL66

4

0

High-throughput

0.664

High

1452660

RM15
Large ribosomal subunit protein uL15m

4

0

High-throughput

0.664

High

1452661

RM27
Large ribosomal subunit protein bL27m

4

0

High-throughput

0.664

High

1452672

RM11
Large ribosomal subunit protein uL11m

4

0

High-throughput

0.664

High

914777

RM12
Large ribosomal subunit protein bL12m

3

1

High-throughput

0.662

High

271107

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

3

0

High-throughput

0.638

High

1196177

RM51
Large ribosomal subunit protein mL51

3

0

High-throughput

0.638

High

1213361

RM02
Large ribosomal subunit protein uL2m

3

0

High-throughput

0.638

High

1281139

RM55
Large ribosomal subunit protein mL55

3

0

High-throughput

0.638

High

1349567

RM30
Large ribosomal subunit protein uL30m

3

0

High-throughput

0.638

High

1382314

RM24
Large ribosomal subunit protein uL24m

3

0

High-throughput

0.638

High

1389025

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

3

0

High-throughput

0.638

High

1391626

RM48
Large ribosomal subunit protein mL48

3

0

High-throughput

0.638

High

1409987

RM34
Large ribosomal subunit protein bL34m

3

0

High-throughput

0.638

High

1410504

RT63
Large ribosomal subunit protein mL63

3

0

High-throughput

0.638

High

1418073

RM32
Large ribosomal subunit protein bL32m

3

0

High-throughput

0.638

High

1418109

RM20
Large ribosomal subunit protein bL20m

3

0

High-throughput

0.638

High

1418209

RM09
Large ribosomal subunit protein bL9m

3

0

High-throughput

0.638

High

1432247

RM46
Large ribosomal subunit protein mL46

3

0

High-throughput

0.638

High

1438595

MRM3
rRNA methyltransferase 3, mitochondrial

3

0

High-throughput

0.638

High

1439607

RM47
Large ribosomal subunit protein uL29m

3

0

High-throughput

0.638

High

1446749

RM40
Large ribosomal subunit protein mL40

3

0

High-throughput

0.638

High

1452659

RM35
Large ribosomal subunit protein bL35m

3

0

High-throughput

0.638

High

1275860

RM21
Large ribosomal subunit protein bL21m

3

0

High-throughput

0.628

High

1419660

RM37
Large ribosomal subunit protein mL37

2

1

High-throughput

0.611

High

1452663

PAK5
Serine/threonine-protein kinase PAK 5

2

0

High-throughput

0.602

High

447519

NPM
Nucleophosmin

2

0

High-throughput

0.585

High

1158316

RM23
Large ribosomal subunit protein uL23m

2

0

High-throughput

0.585

High

1240863

RM14
Large ribosomal subunit protein uL14m

2

0

High-throughput

0.585

High

1309080

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

2

0

High-throughput

0.585

High

284241

SRS10
Serine/arginine-rich splicing factor 10

2

1

Small-scale

0.584

High

1048733

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

1

High-throughput

0.571

High

1209731

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

3

High-throughput

0.571

High

1331702

RM43
Large ribosomal subunit protein mL43

2

0

High-throughput

0.559

High

994841

YBOX1
Y-box-binding protein 1

1

1

High-throughput

0.536

High

1016650

SRSF3
Serine/arginine-rich splicing factor 3

1

2

High-throughput

0.536

High

1027806

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

1033271

EWS
RNA-binding protein EWS

1

2

High-throughput

0.536

High

1148811

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

1

High-throughput

0.536

High

1360095

PALLD
Palladin

1

3

High-throughput

0.536

High

1415561

GNL3
Guanine nucleotide-binding protein-like 3

1

1

High-throughput

0.536

High

1452670

YBOX2
Y-box-binding protein 2

1

1

High-throughput

0.536

High

835769

KPCI
Protein kinase C iota type

2

2

High-throughput

0.521

High

135365

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.513

High

280065

RM33
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.513

High

616023

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

859096

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

964169

RL37
Large ribosomal subunit protein eL37

1

0

High-throughput

0.513

High

1009344

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

1016267

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1039428

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.513

High

1287564

RM52
Large ribosomal subunit protein mL52

1

0

High-throughput

0.513

High

1347108

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.513

High

1389300

RM53
Large ribosomal subunit protein mL53

1

0

High-throughput

0.513

High

1452658

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.513

High

1452668

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

635010

MAK
Serine/threonine-protein kinase MAK

1

1

High-throughput

0.489

High

649446

H1T
Histone H1t

1

1

High-throughput

0.489

High

713472

SPB3
Serpin B3

1

1

High-throughput

0.489

High

724645

S10A7
Protein S100-A7

1

2

High-throughput

0.489

High

874878

SPB4
Serpin B4

1

1

High-throughput

0.489

High

1114473

CUL3
Cullin-3

1

3

High-throughput

0.489

High

1286358

S1A7A
Protein S100-A7A

1

2

High-throughput

0.489

High

1452669

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.489

High

183756

RT12
Small ribosomal subunit protein uS12m

1

1

High-throughput

0.479

High

243137

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

279953

CISY
Citrate synthase, mitochondrial

1

2

High-throughput

0.479

High

282112

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

287399

RF1M
Peptide chain release factor 1, mitochondrial

1

4

High-throughput

0.479

High

412711

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

414734

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

473138

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.479

High

533016

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

799528

BRCA1
Breast cancer type 1 susceptibility protein

1

2

High-throughput

0.479

High

828989

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

856410

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.479

High

882927

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

935200

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

988225

TRA2B
Transformer-2 protein homolog beta

1

3

High-throughput

0.479

High

1058326

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1062681

DHX9
ATP-dependent RNA helicase A

1

2

Small-scale

0.479

High

1083781

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1087595

GRSF1
G-rich sequence factor 1

1

1

High-throughput

0.479

High

1111887

TRA2A
Transformer-2 protein homolog alpha

1

1

High-throughput

0.479

High

1117868

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

2

High-throughput

0.479

High

1127201

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

1138699

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1142689

PDK1
[Pyruvate dehydrogenase

1

1

High-throughput

0.479

High

1194420

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

1229718

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

1234551

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.479

High

1240349

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.479

High

1273016

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

1275722

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

2

High-throughput

0.479

High

1310472

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.479

High

1335006

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

1381131

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

3

High-throughput

0.479

High

1381754

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1388296

RRFM
Ribosome-recycling factor, mitochondrial

1

1

High-throughput

0.479

High

1401642

EFGM
Elongation factor G, mitochondrial

1

3

High-throughput

0.479

High

1413030

MTG1
Mitochondrial ribosome-associated GTPase 1

1

1

High-throughput

0.479

High

1416568

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

2

High-throughput

0.479

High

1432638

MTRFR
Mitochondrial translation release factor in rescue

1

4

High-throughput

0.479

High

1433741

MTG2
Mitochondrial ribosome-associated GTPase 2

1

2

High-throughput

0.479

High

1435811

MET17
Ribosome assembly protein METTL17, mitochondrial

1

2

High-throughput

0.479

High

1450450

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

1452656

RM39
Large ribosomal subunit protein mL39

1

8

High-throughput

0.479

High

1452657

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

3

High-throughput

0.479

High

1452662

MRES1
Mitochondrial transcription rescue factor 1

1

1

High-throughput

0.479

High

1452664

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

4

High-throughput

0.479

High

66316

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

326786

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.458

High

485466

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

538019

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

694031

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

841997

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852060

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

1149643

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1152657

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.458

High

1215867

RC3H1
Roquin-1

1

0

High-throughput

0.458

High

1228340

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.458

High

1270661

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1360686

SYNE2
Nesprin-2

1

0

High-throughput

0.458

High

1384894

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1406932

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.458

High

1412464

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1414106

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1415692

TR61B
tRNA

1

0

High-throughput

0.458

High

1418911

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1429808

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

1431982

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1436117

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1451262

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1451453

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1451695

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

0

High-throughput

0.458

High

1452674

DJC15
DnaJ homolog subfamily C member 15

1

0

High-throughput

0.458

High

216994

KLF4
Krueppel-like factor 4

1

1

High-throughput

0.457

High

430438

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

1024213

TFAM
Transcription factor A, mitochondrial

1

1

High-throughput

0.445

High

1214819

ATD3B
ATPase family AAA domain-containing protein 3B

1

4

High-throughput

0.445

High

1400829

TEFM
Transcription elongation factor, mitochondrial

1

1

Small-scale

0.445

High

1411184

RM45
Large ribosomal subunit protein mL45

1

1

High-throughput

0.445

High

1450580

ATD3A
ATPase family AAA domain-containing protein 3A

1

4

High-throughput

0.445

High

316082

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

373328

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

406730

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.437

High

971193

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1015849

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.437

High

1051328

KPCZ
Protein kinase C zeta type

1

2

High-throughput

0.437

High

1187990

GON4L
GON-4-like protein

1

1

High-throughput

0.437

High

1250531

RBP10
Ran-binding protein 10

1

2

High-throughput

0.437

High

1255838

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1322547

MIER1
Mesoderm induction early response protein 1

1

1

High-throughput

0.437

High

1368650

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.437

High

1434070

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

1445895

HM20A
High mobility group protein 20A

1

1

High-throughput

0.437

High

1447353

ANLN
Anillin

1

1

High-throughput

0.437

High

1452665

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1452666

XPO7
Exportin-7

1

2

High-throughput

0.437

High

1452673

MAFB
Transcription factor MafB

1

4

High-throughput

0.437

High

1452675

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

1307938

ARMC8
Armadillo repeat-containing protein 8

3

0

High-throughput

0.347

High

872815

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.279

Low

1159426

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

1197578

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.279

Low

1260450

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

1291246

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.279

Low

1338638

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

0

High-throughput

0.279

Low

1452667

TEKT2
Tektin-2

1

0

High-throughput

0.279

Low

320361

PHF14
PHD finger protein 14

1

0

High-throughput

0.249

Low

587529

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.249

Low

879544

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

957530

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.249

Low

1106382

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

0

High-throughput

0.249

Low

1309318

GID4
Glucose-induced degradation protein 4 homolog

1

0

High-throughput

0.249

Low

1380672

FBX32
F-box only protein 32

1

0

High-throughput

0.249

Low

1431664

GAN
Gigaxonin

1

0

High-throughput

0.249

Low

1436198

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

High-throughput

0.249

Low

1438927

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.249

Low

1446976

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.249

Low

1105251

S39A6
Zinc transporter ZIP6

1

0

High-throughput

0.232

Low

1214207

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

1242255

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025