Interactor 1: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Interactor 2: SPAT2 (Q9UM82)
Spermatogenesis-associated protein 2
Gene: SPATA2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 27458237, 27591049, 27307491, 27545878, 31762063, 36180997, 36640323, 19615732, 31067453, 24981860
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0010803 - regulation of tumor necrosis factor-mediated signaling pathway
GO:0050727 - regulation of inflammatory response
GO:0060544 - regulation of necroptotic process
GO:0070266 - necroptotic process
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 956
Hs

1 520
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024