HitPredict

Interactor 1: EXOS3 (Q9NQT5)
Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10)
Gene: EXOSC3

Interactor 2: RRP44 (Q9Y2L1)
Exosome complex exonuclease RRP44 (EC 3.1.13.-) (EC 3.1.26.-) (Protein DIS3 homolog) (Ribosomal RNA-processing protein 44)
Gene: DIS3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

The method score is based on:

Property	Details
Experiments	33961781, 20531389, 21255825
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000175 - 3'-5'-RNA exonuclease activity GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding and 7 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006364 - rRNA processing GO:0006396 - RNA processing GO:0006401 - RNA catabolic process GO:0071034 - CUT catabolic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	275
Hs

1	958

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024