Protein: PRS8
26S proteasome regulatory subunit 8

Gene: PRS8, Rpt6
Organism: Drosophila melanogaster
Interactions: 113
UniProt ID: O18413

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

198028

PSA2
Proteasome subunit alpha type-2

3

20

High-throughput

0.812

High

198032

PRS4
26S proteasome regulatory subunit 4

3

18

High-throughput

0.812

High

198050

Q7KMQ0
26S proteasome regulatory subunit 7

3

19

High-throughput

0.812

High

198090

Q9VJJ0
Proteasome subunit beta

3

20

High-throughput

0.812

High

198117

Q9W414
Regulatory particle triple-A ATPase 4

3

19

High-throughput

0.812

High

198118

PSB3
Proteasome subunit beta type-3

3

20

High-throughput

0.812

High

47735

A0AQH0
Proteasome subunit beta

2

20

High-throughput

0.737

High

198018

PSA1
Proteasome subunit alpha type-1

2

20

High-throughput

0.737

High

198020

PSA4
Proteasome subunit alpha type-4

2

20

High-throughput

0.737

High

198021

PSA71
Proteasome subunit alpha type-7-1

2

20

High-throughput

0.737

High

198024

PSMD7
26S proteasome non-ATPase regulatory subunit 7

2

20

High-throughput

0.737

High

198029

PSB1
Proteasome subunit beta type-1

2

20

High-throughput

0.737

High

198042

Q7K148
Proteasome subunit beta

2

20

High-throughput

0.737

High

198060

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.737

High

198064

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

20

High-throughput

0.737

High

198066

Q9V3V6
26S proteasome regulatory complex subunit p50

2

17

High-throughput

0.737

High

198068

Q9V405
26S proteasome regulatory subunit 6B

2

17

High-throughput

0.737

High

198072

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.737

High

198093

PSB4
Proteasome subunit beta type-4

2

20

High-throughput

0.737

High

198102

Q9VUJ1
Proteasome subunit beta

2

20

High-throughput

0.737

High

198105

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

2

20

High-throughput

0.737

High

198106

Q9VWD9
Ubiquilin-like protein

1

20

Small-scale

0.647

High

198063

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

20

High-throughput

0.618

High

198067

Q9V3Z4
GH11341p

1

20

High-throughput

0.618

High

198119

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.618

High

198055

Q8IRD1
AAA+ ATPase domain-containing protein

1

17

High-throughput

0.590

High

198056

Q8T8V8
Proteasome subunit beta

1

20

High-throughput

0.590

High

198083

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

9

High-throughput

0.590

High

198088

NEDD8
Ubiquitin-like protein NEDD8

1

16

High-throughput

0.590

High

198101

Q9VTQ9
AT06668p

1

19

High-throughput

0.590

High

198109

Q9VXF9
AT13091p

1

20

High-throughput

0.590

High

198058

Q8WS79
Estrogen-related receptor splice variant

2

20

High-throughput

0.584

High

198099

Q9VSE9
Estrogen-related receptor

2

20

High-throughput

0.584

High

198023

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

2

13

High-throughput

0.571

High

198033

TCPG
T-complex protein 1 subunit gamma

2

9

High-throughput

0.571

High

198043

ADRM1
Proteasomal ubiquitin receptor ADRM1 homolog

2

10

High-throughput

0.571

High

198047

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

20

High-throughput

0.571

High

198049

Q7KMP8
26S proteasome non-ATPase regulatory subunit 13

2

13

High-throughput

0.571

High

198065

PSMD1
26S proteasome non-ATPase regulatory subunit 1

2

20

High-throughput

0.571

High

198071

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

7

High-throughput

0.571

High

198073

Q9V9Q4
LD43819p

2

5

High-throughput

0.571

High

198075

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

4

High-throughput

0.571

High

198084

Q9VFV9
DnaJ-like-2, isoform A

2

5

High-throughput

0.571

High

198091

Q9VK69
T-complex protein 1 subunit delta

2

4

High-throughput

0.571

High

198092

NFS1
Cysteine desulfurase, mitochondrial

2

4

High-throughput

0.571

High

198111

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

4

High-throughput

0.571

High

198115

Q9W392
T-complex protein 1 subunit beta

2

10

High-throughput

0.571

High

198121

X2JLM6
Ubiquitin carboxyl-terminal hydrolase

1

7

Small-scale

0.553

High

198026

FAS2
Fasciclin-2

1

3

High-throughput

0.536

High

198085

Q9VGU4
FI02822p

1

8

High-throughput

0.536

High

198025

CLH
Clathrin heavy chain

2

3

High-throughput

0.521

High

198051

Q7KN94
Electron transfer flavoprotein subunit alpha

2

4

High-throughput

0.521

High

198089

Q9VJD1
Glucosidase 2 subunit beta

2

3

High-throughput

0.521

High

198104

Q9VV75
AT02348p

2

3

High-throughput

0.521

High

198107

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

4

High-throughput

0.521

High

198014

O77135
FI03211p

1

1

High-throughput

0.508

High

198031

ARP6
Actin-related protein 6

1

5

High-throughput

0.508

High

198120

TFP11
Septin-interacting protein 1

1

1

High-throughput

0.508

High

198022

ODD
Protein odd-skipped

1

0

High-throughput

0.486

High

120548

M9PDL4
Multiple wing hairs, isoform B

1

4

High-throughput

0.481

High

198016

TPM1
Tropomyosin-1, isoforms 9A/A/B

1

6

High-throughput

0.481

High

198039

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

9

High-throughput

0.479

High

198044

Q7K3J0
T-complex protein 1 subunit theta

1

8

High-throughput

0.479

High

198045

IMD
Protein immune deficiency

1

1

Small-scale

0.479

High

198054

AKT1
RAC serine/threonine-protein kinase

1

6

High-throughput

0.479

High

198059

LDH
L-lactate dehydrogenase

1

5

High-throughput

0.479

High

198077

ATLAS
Atlastin

1

2

Small-scale

0.479

High

198082

Q9VEC2
Proteasome assembly chaperone 2

1

5

High-throughput

0.479

High

198087

Q9VIJ5
GEO05038p1

1

4

High-throughput

0.479

High

198096

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

2

High-throughput

0.479

High

198114

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

13

High-throughput

0.479

High

198035

CNN
Centrosomin

1

2

High-throughput

0.464

High

198013

RAD54
DNA repair and recombination protein RAD54-like

1

3

High-throughput

0.457

High

198113

Q9W0J2
Multiple wing hairs, isoform A

1

4

High-throughput

0.457

High

198053

Q8IG84
SD21996p

1

4

High-throughput

0.451

High

198019

REF2P
Protein ref(2)P

1

2

High-throughput

0.445

High

198027

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

4

High-throughput

0.445

High

198030

ARF4
ADP ribosylation factor 4

1

5

High-throughput

0.445

High

198034

PFKA
ATP-dependent 6-phosphofructokinase

1

3

High-throughput

0.445

High

198036

ROP
Protein ROP

1

5

High-throughput

0.445

High

198037

Q0E9E2
Pyruvate carboxylase

1

4

High-throughput

0.445

High

198038

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

4

High-throughput

0.445

High

198057

Q8T8W3
AT21416p

1

4

High-throughput

0.445

High

198061

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

7

High-throughput

0.445

High

198069

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

6

High-throughput

0.445

High

198070

Q9V455
Importin subunit alpha

1

5

High-throughput

0.445

High

198074

Q9VAH7
N-terminal kinase-like protein

1

3

High-throughput

0.445

High

198086

Q9VHL2
T-complex protein 1 subunit eta

1

5

High-throughput

0.445

High

198095

NUBP2
Cytosolic Fe-S cluster assembly factor Nubp2 homolog

1

1

High-throughput

0.445

High

198097

Q9VQL1
serine--tRNA ligase

1

4

High-throughput

0.445

High

198098

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

3

High-throughput

0.445

High

198112

Q9W0E4
Aminopeptidase

1

5

High-throughput

0.445

High

52629

A1Z729
NADP-retinol dehydrogenase

1

11

High-throughput

0.437

High

198041

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

9

High-throughput

0.437

High

198048

Q7KLX3
Translocon-associated protein subunit delta

1

2

High-throughput

0.437

High

198094

Q9VNI4
Proteasome assembly chaperone 1

1

4

High-throughput

0.437

High

198108

Q9VWL0
Mec2

1

5

High-throughput

0.437

High

144850

ATPG
ATP synthase subunit gamma, mitochondrial

1

4

High-throughput

0.407

High

198015

COX2
Cytochrome c oxidase subunit 2

1

4

High-throughput

0.407

High

198017

RAS1
Ras-like protein 1

1

4

High-throughput

0.407

High

198040

Q6NP72
GEO09659p1

1

3

High-throughput

0.407

High

198046

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.407

High

198052

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

4

High-throughput

0.407

High

198062

Q960C7
NADP-retinol dehydrogenase

1

11

High-throughput

0.407

High

198100

SRP68
Signal recognition particle subunit SRP68

1

4

High-throughput

0.407

High

198103

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

6

High-throughput

0.407

High

198110

Q9VXG0
Cell division cycle 50, isoform A

1

4

High-throughput

0.407

High

198116

Q9W3N1
RH59310p

1

3

High-throughput

0.407

High

198079

BECN1
Beclin-1-like protein

3

0

High-throughput

0.340

High

198078

Q9VC66
AT25567p

2

0

High-throughput

0.310

High

198076

Q9VAY6
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.265

Low

198081

CPSF3
Cleavage and polyadenylation specificity factor 73

1

0

High-throughput

0.265

Low

198080

Q9VCF8
LD23561p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025