HitPredict

Interactor 1: TLR8 (Q9NR97)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Interactor 2: TLR7 (Q9NYK1)
Toll-like receptor 7
Gene: TLR7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17040905
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, TIR~TIR
Common GO terms GO:0000139 - Golgi membrane
GO:0001932 - regulation of protein phosphorylation
GO:0002224 - toll-like receptor signaling pathway
GO:0003725 - double-stranded RNA binding
GO:0003727 - single-stranded RNA binding
and 15 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1041
Hs

1 1049
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Last updated: 15 Jul 2024