HitPredict

Interactor 1: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Interactor 2: PLXA1 (Q9UIW2)
Plexin-A1 (Semaphorin receptor NOV)
Gene: PLXNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 22268729
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 1896
+	Hs
		1355914 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PLXA1_HUMAN (1-1896): 0: 2610: 100.00
+	Hs
		253506 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PLXA2_HUMAN (34-1896): 0: 2410: 63.96
+	Hs
		850510 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PLXA3_HUMAN (39-1896): 0: 2343: 67.15
+	Hs
		165258 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		PLXB2_HUMAN (38-1893): 0: 1949: 32.31
+	Hs
		165268 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PLXB2_HUMAN (38-1893): 0: 1949: 32.31
+	Hs
		1356253 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PLXD1_HUMAN (45-1893): 0: 1846: 31.33
+	Hs
		1318976 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		SEM4C_HUMAN (3-575): 5.72e-123: 411: 20.29
+	Hs
		441570 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		MET_HUMAN (814-1212): 1.56e-103: 367: 25.80
+	Hs
		981927 FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00		RON_HUMAN (815-1212): 5.65e-85: 310: 25.24
+	Hs
		1343021 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		SEM4B_HUMAN (23-769): 2.82e-124: 414: 16.45
+	Hs
		1318984 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		SEM4C_HUMAN (3-575): 5.72e-123: 411: 20.29
+	Hs
		1329267 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		SEM6A_HUMAN (6-549): 2.71e-119: 406: 16.36
+	Hs
		1307502 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		SEM3C_HUMAN (40-545): 1.06e-121: 404: 15.43
+	Hs
		234730 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		PLXC1_HUMAN (63-906): 9.29e-111: 391: 18.38
+	Hs
		441579 FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17		MET_HUMAN (814-1212): 1.56e-103: 367: 25.80