HitPredict

Interactor 1: CTNA2 (P26232)
Catenin alpha-2 (Alpha N-catenin) (Alpha-catenin-related protein)
Gene: CTNNA2

Interactor 2: CADH5 (P33151)
Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: CDH5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005912 - adherens junction GO:0008013 - beta-catenin binding GO:0016342 - catenin complex GO:0045296 - cadherin binding GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 953 Hs			1 784
+	Hs
		702744 CTNA1_HUMAN (8-952): 0: 949: 78.12		CADH5_HUMAN (1-784): 0: 794: 100.00
+	Mm
		640688 CTNA1_MOUSE (8-952): 0: 946: 78.12		CADH5_MOUSE (1-783): 0: 750: 74.68
+	Hs
		521735 CTNA2_HUMAN (1-953): 0: 1082: 100.00		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Hs
		716725 CTNA1_HUMAN (8-952): 0: 949: 78.12		CAD24_HUMAN (1-782): 0: 684: 35.90
+	Hs
		1199809 CTNA3_HUMAN (3-949): 0: 910: 57.55		CAD24_HUMAN (1-782): 0: 684: 35.90
+	Hs
		521757 CTNA1_HUMAN (8-952): 0: 949: 78.12		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Mm
		454942 CTNA1_MOUSE (8-952): 0: 946: 78.12		CADH1_MOUSE (25-780): 0: 582: 30.99
+	Hs
		606300 CTNA1_HUMAN (8-952): 0: 949: 78.12		CADH3_HUMAN (32-780): 0: 574: 30.49
+	Hs
		522254 CTNA3_HUMAN (3-949): 0: 910: 57.55		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Hs
		606311 CTNA3_HUMAN (3-949): 0: 910: 57.55		CADH3_HUMAN (32-780): 0: 574: 30.49
+	Hs
		640714 CTNA2_HUMAN (1-953): 0: 1082: 100.00		CAD12_HUMAN (1-469): 7.9e-89: 298: 23.46
+	Hs
		640713 CTNA2_HUMAN (1-953): 0: 1082: 100.00		CADH8_HUMAN (1-469): 2.58e-86: 292: 22.75
+	Hs
		716641 CTNA1_HUMAN (8-952): 0: 949: 78.12		CAD12_HUMAN (1-469): 7.9e-89: 298: 23.46
+	Hs
		716640 CTNA1_HUMAN (8-952): 0: 949: 78.12		CADH8_HUMAN (1-469): 2.58e-86: 292: 22.75
+	Hs
		877559 CTNA3_HUMAN (3-949): 0: 910: 57.55		CAD12_HUMAN (1-469): 7.9e-89: 298: 23.46
+	Hs
		1355726 CTNA3_HUMAN (3-949): 0: 910: 57.55		CAD10_HUMAN (1-469): 5.1e-88: 296: 24.50
+	Hs
		521714 VINC_HUMAN (15-911): 0: 586: 19.92		CADH1_HUMAN (26-780): 0: 590: 31.71
+	Hs
		580206 CTNA1_HUMAN (8-952): 0: 949: 78.12		CADH2_HUMAN (1-469): 4.36e-61: 224: 20.67
+	Hs
		877527 CTNA3_HUMAN (3-949): 0: 910: 57.55		CADH4_HUMAN (1-475): 6.52e-65: 235: 19.88
+	Hs
		580266 CTNA3_HUMAN (3-949): 0: 910: 57.55		CADH2_HUMAN (1-469): 4.36e-61: 224: 20.67