HitPredict

Interactor 1: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Interactor 2: JAM1 (Q9Y624)
Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet F11 receptor) (Platelet adhesion molecule 1) (PAM-1) (CD antigen CD321)
Gene: F11R

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	26186194, 28514442, 33961781, 15811349
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 415 Hs			1 299
+	Mm
		292318 PICK1_MOUSE (1-415): 0: 584: 94.47		JAM1_MOUSE (1-299): 5.56e-63: 202: 67.11
+	Hs
		1314999 PICK1_HUMAN (1-415): 0: 592: 100.00		JAM3_HUMAN (27-299): 5.24e-51: 172: 32.27
+	Hs
		883801 PICK1_HUMAN (1-415): 0: 592: 100.00		JAM2_HUMAN (18-299): 4.69e-51: 171: 33.33
+	Mm
		1143301 PICK1_MOUSE (1-415): 0: 584: 94.47		JAM3_MOUSE (27-299): 1.74e-48: 165: 32.62
+	Hs
		1298003 PICK1_HUMAN (1-415): 0: 592: 100.00		ROBO3_HUMAN (2-150): 9.28e-17: 82.6: 16.77
+	Hs
		609429 ICA1L_HUMAN (143-387): 1.08e-74: 242: 14.92		FGFR3_HUMAN (37-126): 6.28e-11: 64.8: 16.84