HitPredict

Interactor 1: RASF1 (Q9NS23)
Ras association domain-containing protein 1
Gene: RASSF1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	25900982, 28514442, 33961781, 21900206, 21910689
Identification Methods	proximity labelling technology, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0051726 - regulation of cell cycle
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 605
+	Hs
		1262943 RASF5_HUMAN (11-339): 8.08e-111: 330: 43.23		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		3292 RASF5_HUMAN (11-339): 8.08e-111: 330: 43.23		A0A0S2Z507_HUMAN (1-605): 0: 534: 95.13
+	Hs
		1345288 RASF1_HUMAN (1-344): 7.96e-150: 427: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1203204 RASF3_HUMAN (118-339): 2.62e-59: 192: 44.44		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1068522 KPCD1_HUMAN (50-183): 2.44e-19: 91: 19.40		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1203203 RASF3_HUMAN (118-339): 2.62e-59: 192: 44.44		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Mm
		593490 KPCA_MOUSE (24-281): 1.76e-33: 132: 12.04		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71
+	Mm
		934635 KPCB_MOUSE (24-283): 3.51e-33: 131: 15.02		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71
+	Mm
		973813 KPCZ_MOUSE (15-152): 4.36e-33: 131: 24.11		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71
+	Mm
		554925 KPCE_MOUSE (27-107): 4.01e-13: 72.2: 31.33		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71