HitPredict

Interactor 1: PEX12 (O00623)
Peroxisome assembly protein 12 (Peroxin-12) (Peroxisome assembly factor 3) (PAF-3)
Gene: PEX12

Interactor 2: PEX5 (P50542)
Peroxisomal targeting signal 1 receptor (PTS1 receptor) (PTS1R) (PTS1-BP) (Peroxin-5) (Peroxisomal C-terminal targeting signal import receptor) (Peroxisome receptor 1)
Gene: PEX5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

The method score is based on:

Property	Details
Experiments	10562279, 10837480, 12456682, 12096124, 30378028, 22002062
Identification Methods	two hybrid, pull down, affinity chromatography technology, filter binding, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005777 - peroxisome GO:0005778 - peroxisomal membrane GO:0005829 - cytosol GO:0006625 - protein targeting to peroxisome GO:0016558 - protein import into peroxisome matrix and 3 others more... GO:0016562 - protein import into peroxisome matrix, receptor recycling GO:0034614 - cellular response to reactive oxygen species GO:0044721 - protein import into peroxisome matrix, substrate release
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	359
Hs

1	639

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024