HitPredict

Interactor 1: PUF68 (Q8T6B9)
Poly(U)-binding-splicing factor hfp (68 kDa poly(U)-binding-splicing factor) (PUF60 homolog) (Protein half pint)
Gene: hfp

Interactor 2: Q9V3Y5 (Q9V3Y5)
BcDNA.LD23634 (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B)
Gene: BcDNA.LD23634

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0071011 - precatalytic spliceosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 637 Dm			1 998
+	Dm
		1275245 PUF68_DROME (1-637): 4.64e-108: 341: 100.00		Q7YZ99_DROME (108-713): 1.39e-11: 71: 11.89
+	Hs
		1101981 PABP4_HUMAN (541-637): 2.6e-10: 65.5: 15.46		HYDIN_HUMAN (302-741): 4.46e-19: 95.7: 10.86
+	Hs
		1102027 PABP4_HUMAN (541-637): 2.6e-10: 65.5: 15.46		RBCC1_HUMAN (112-643): 3.44e-13: 76.3: 12.78
+	Hs
		550373 PABP1_HUMAN (541-637): 2.98e-10: 65.1: 16.50		RBCC1_HUMAN (112-643): 3.44e-13: 76.3: 12.78