Protein: PUF68
Poly(U)-binding-splicing factor hfp (68 kDa poly(U)-binding-splicing factor) (PUF60 homolog) (Protein half pint)

Gene: PUF68, hfp
Organism: Drosophila melanogaster
Interactions: 84
UniProt ID: Q8T6B9

Gene Ontology (top 5):
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0001558 - regulation of cell growth
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

599461

ELAV
Protein elav

2

15

High-throughput

0.767

High

1346135

Q9VGH5
AT27789p

2

19

Small-scale

0.754

High

602162

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

18

High-throughput

0.737

High

1346121

Q9V3Y5
BcDNA.LD23634

2

4

High-throughput

0.737

High

1346143

Q9VL71
LD29830p

2

11

High-throughput

0.737

High

1346138

Q9VIY9
IP01252p

1

0

High-throughput

0.622

High

877805

RB27C
Heterogeneous nuclear ribonucleoprotein 27C

1

20

Small-scale

0.618

High

1346122

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.618

High

660454

CDK2
Cyclin-dependent kinase 2

1

7

High-throughput

0.590

High

1346169

Q9Y145
Serine/threonine-protein kinase PRP4 homolog

1

13

High-throughput

0.575

High

1346151

Q9VQK5
LD24714p

2

15

High-throughput

0.571

High

304866

E2F2
Transcription factor E2F2

1

1

High-throughput

0.508

High

632463

CCNB
G2/mitotic-specific cyclin-B

1

1

High-throughput

0.508

High

654295

DDX6
ATP-dependent RNA helicase me31b

1

17

High-throughput

0.508

High

1197199

RBP9X
Ran-binding proteins 9/10 homolog

1

4

High-throughput

0.508

High

1345790

SINAL
Probable E3 ubiquitin-protein ligase sinah

1

5

High-throughput

0.508

High

1346142

PIE
Pineapple eye protein

1

2

High-throughput

0.508

High

1346167

Q9W396
FI06908p

1

1

High-throughput

0.508

High

895391

RUX
Cell cycle negative regulator roughex

1

0

High-throughput

0.486

High

913215

TF2AA
Transcription initiation factor IIA subunit 1

1

0

High-throughput

0.486

High

1176907

PHYL
Protein phyllopod

1

0

High-throughput

0.486

High

1320671

Q8MLP8
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.486

High

1346126

Q9VBK9
Protein FAM98B

1

0

High-throughput

0.486

High

1346154

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.486

High

1346157

Q9VW52
Precursor RNA processing 3, isoform A

1

0

High-throughput

0.486

High

1039158

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

7

Small-scale

0.479

High

1275245

Q7YZ99
Serine-arginine repetitive matrix 2/3/4, isoform A

1

8

High-throughput

0.479

High

1346127

Q9VCC9
LD23779p

1

7

High-throughput

0.479

High

534452

ACT1
Actin-5C

1

5

High-throughput

0.464

High

715119

CLH
Clathrin heavy chain

1

1

High-throughput

0.464

High

1019610

TRXR1
Thioredoxin reductase 1, mitochondrial

1

2

High-throughput

0.464

High

1344861

Q8SZP2
RE71854p

1

2

High-throughput

0.464

High

1346131

Q9VDC3
AP complex subunit sigma

1

3

High-throughput

0.464

High

1346133

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.464

High

1346136

Q9VHA5
GH19763p

1

1

High-throughput

0.464

High

1172623

SIMA
Protein similar

1

0

High-throughput

0.458

High

1346145

TCP4
RNA polymerase II transcriptional coactivator

1

0

High-throughput

0.458

High

1346166

Q9W1G7
LD21576p

1

0

High-throughput

0.458

High

583690

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

6

High-throughput

0.457

High

1346160

Q9VXF9
AT13091p

1

8

High-throughput

0.457

High

1265949

DHX15
ATP-dependent RNA helicase DHX15 homolog

1

3

High-throughput

0.445

High

1346117

Q961D1
Cyclin-K

1

5

High-throughput

0.445

High

1346125

NKAP
NF-kappa-B-activating protein

1

1

High-throughput

0.445

High

1346132

Q9VES0
FI23980p1

1

2

High-throughput

0.445

High

1346137

Q9VI14
GH12404p

1

6

High-throughput

0.445

High

1346139

Q9VIZ3
RNA helicase

1

3

High-throughput

0.445

High

1346141

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2 homolog

1

1

High-throughput

0.445

High

1346144

PESC
Pescadillo homolog

1

1

High-throughput

0.445

High

1346156

LUC7L
Putative RNA-binding protein Alsin2

1

3

High-throughput

0.445

High

1261749

Q7JR91
GH12715p

1

2

High-throughput

0.439

High

1346161

Q9VXR9
FI03680p

1

2

High-throughput

0.439

High

1346170

X2JCR2
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

652756

PSA71
Proteasome subunit alpha type-7-1

1

0

High-throughput

0.438

High

1346124

Q9VAX9
MIP05919p

1

0

High-throughput

0.426

High

1346134

Q9VG84
DNA ligase

1

0

High-throughput

0.426

High

1069260

Q0E8G5
Uncharacterized protein, isoform D

1

1

High-throughput

0.417

High

1346116

Q95T37
GH26622p

1

2

High-throughput

0.417

High

1346118

Q961V9
GH03273p

1

2

High-throughput

0.417

High

1346129

Q9VCD5
UV excision repair protein RAD23

1

13

High-throughput

0.417

High

1346159

Q9VWD9
Ubiquilin-like protein

1

8

High-throughput

0.417

High

1346115

NACA
Nascent polypeptide-associated complex subunit alpha

1

2

High-throughput

0.407

High

1346146

Q9VMI5
CG9135 protein

1

3

High-throughput

0.407

High

1346149

Q9VQ94
LP05220p

1

1

High-throughput

0.407

High

1346163

Q9VYW4
ATP-binding cassette sub-family F member 1

1

1

High-throughput

0.407

High

57360

A1ZAZ7
XK-related protein

1

0

High-throughput

0.265

Low

1321119

Q8MRM0
GH16740p

1

0

High-throughput

0.265

Low

1346120

Q9V3U6
26-29kD-proteinase

1

0

High-throughput

0.265

Low

1346123

Q9VAU6
LD27564p

1

0

High-throughput

0.265

Low

1346130

Q9VCZ7
Uncharacterized protein

1

0

High-throughput

0.265

Low

1346148

Q9VPN8
Peptidase S1 domain-containing protein

1

0

High-throughput

0.265

Low

1346150

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.265

Low

1346152

Q9VS81
Uncharacterized protein

1

0

High-throughput

0.265

Low

1346153

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.265

Low

1346155

Q9VV44
Cuticular protein 72Ea

1

0

High-throughput

0.265

Low

1346162

Q9VY49
LD24340p

1

0

High-throughput

0.265

Low

1346168

Q9XZ68
Geranylgeranyl transferase type-2 subunit beta

1

0

High-throughput

0.265

Low

122402

M9PJG3
Uncharacterized protein, isoform C

1

0

High-throughput

0.251

Low

1346140

XPP
Xaa-Pro aminopeptidase ApepP

1

0

High-throughput

0.249

Low

1346147

TOTM
Protein Turandot M

1

0

High-throughput

0.238

Low

1346119

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

1

0

High-throughput

0.232

Low

1346128

Q9VCD4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

0

High-throughput

0.232

Low

1346158

Q9VW70
FI21813p1

1

0

High-throughput

0.232

Low

1346164

Q9VZP5
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.232

Low

1346165

Q9W019
IP09724p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025