Interactor 1: MED17 (Q9NVC6)
Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)
Gene: MED17

Interactor 2: MED29 (Q9NX70)
Mediator of RNA polymerase II transcription subunit 29 (Intersex-like protein) (Mediator complex subunit 29)
Gene: MED29

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.751

The method score is based on:

Property Details
Experiments 24981860, 33961781, 35271311, 15175163, 14638676, 14576168, 15989967
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
and 4 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 651
Hs

1 200
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024