Protein: MESD
LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development LRP chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein) (Renal carcinoma antigen NY-REN-61)

Gene: MESD
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q14696

Gene Ontology (top 5):
GO:0001503 - ossification
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0006457 - protein folding
GO:0006909 - phagocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1131178

CL12A
C-type lectin domain family 12 member A

3

0

High-throughput

0.638

High

1131216

ARSG
Arylsulfatase G

2

5

High-throughput

0.628

High

582333

ARSA
Arylsulfatase A

3

5

High-throughput

0.609

High

647354

IDS
Iduronate 2-sulfatase

3

5

High-throughput

0.609

High

1131220

WDFY2
WD repeat and FYVE domain-containing protein 2

3

1

High-throughput

0.609

High

684240

DDX6
Probable ATP-dependent RNA helicase DDX6

2

1

High-throughput

0.606

High

1131249

UBQL1
Ubiquilin-1

2

1

High-throughput

0.606

High

1131248

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

2

0

High-throughput

0.602

High

472173

TRFM
Melanotransferrin

2

0

High-throughput

0.580

High

553425

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

2

0

High-throughput

0.580

High

728241

AKT1
RAC-alpha serine/threonine-protein kinase

2

0

High-throughput

0.580

High

933838

GEM
GTP-binding protein GEM

2

0

High-throughput

0.580

High

1131203

ARB2A
Cotranscriptional regulator ARB2A

2

0

High-throughput

0.580

High

1131227

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.580

High

1131228

ABCG8
ATP-binding cassette sub-family G member 8

2

0

High-throughput

0.580

High

1131254

LY96
Lymphocyte antigen 96

2

0

High-throughput

0.580

High

465962

CO1A2
Collagen alpha-2(I) chain

2

2

High-throughput

0.553

High

1043623

COAA1

2

3

High-throughput

0.553

High

1086588

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

1

High-throughput

0.553

High

1131213

VATE2
V-type proton ATPase subunit E 2

2

1

High-throughput

0.553

High

456942

CO8A
Complement component C8 alpha chain

1

1

High-throughput

0.536

High

1131192

MILR1
Allergin-1

1

1

High-throughput

0.536

High

529804

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

854434

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

0

High-throughput

0.513

High

880007

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.513

High

1102939

ITAD
Integrin alpha-D

1

0

High-throughput

0.513

High

1131252

RPGF2
Rap guanine nucleotide exchange factor 2

1

0

High-throughput

0.513

High

477235

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

1

High-throughput

0.500

High

620370

NUCL
Nucleolin

1

0

High-throughput

0.493

High

692965

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

756548

GALNS
N-acetylgalactosamine-6-sulfatase

1

5

High-throughput

0.489

High

1131187

ARSK
Arylsulfatase K

1

5

High-throughput

0.489

High

1131204

ANR49
Ankyrin repeat domain-containing protein 49

1

1

High-throughput

0.489

High

1131236

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.489

High

1131240

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

High-throughput

0.489

High

869741

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.486

High

422109

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

229713

CALU
Calumenin

1

2

High-throughput

0.479

High

566672

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.479

High

720226

UFO
Tyrosine-protein kinase receptor UFO

1

2

High-throughput

0.479

High

1131177

EPHAA
Ephrin type-A receptor 10

1

1

High-throughput

0.479

High

1131219

CALR3
Calreticulin-3

1

1

High-throughput

0.479

High

1131243

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

1131246

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1131173

H2B2E
Histone H2B type 2-E

1

2

High-throughput

0.470

High

1131205

SYNE2
Nesprin-2

1

1

High-throughput

0.470

High

2067

A0A0B4J1Y2
Tetratricopeptide repeat domain 21A

1

1

High-throughput

0.470

High

856694

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.470

High

784788

VATE1
V-type proton ATPase subunit E 1

1

1

High-throughput

0.464

High

1131253

SNX5
Sorting nexin-5

1

1

High-throughput

0.464

High

1131182

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.460

High

1131235

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

0

High-throughput

0.460

High

218186

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

947188

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

951150

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

1131214

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1131231

JUPI2
Jupiter microtubule associated homolog 2

1

0

High-throughput

0.458

High

1131239

T106B
Transmembrane protein 106B

1

0

High-throughput

0.458

High

1131200

TT21A
Tetratricopeptide repeat protein 21A

1

1

High-throughput

0.439

High

1131250

SNX7
Sorting nexin-7

1

1

High-throughput

0.439

High

256857

H2B1K
Histone H2B type 1-K

1

2

High-throughput

0.437

High

460820

CATB
Cathepsin B

1

1

High-throughput

0.437

High

1131188

SYNE3
Nesprin-3

1

1

High-throughput

0.437

High

1131211

H2B1H
Histone H2B type 1-H

1

2

High-throughput

0.437

High

708966

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.328

High

91648

HSBPL
Heat shock factor-binding protein 1-like protein 1

2

0

High-throughput

0.316

High

191912

MAGB4
Melanoma-associated antigen B4

2

0

High-throughput

0.316

High

334412

SYFM
Phenylalanine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

420281

IGF1
Insulin-like growth factor 1

2

0

High-throughput

0.316

High

464155

TPM2
Tropomyosin beta chain

2

0

High-throughput

0.316

High

504896

H2AB2
Histone H2A-Bbd type 2/3

2

0

High-throughput

0.316

High

627127

TYPH
Thymidine phosphorylase

2

0

High-throughput

0.316

High

634108

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

2

0

High-throughput

0.316

High

868165

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.316

High

943647

SIK1
Serine/threonine-protein kinase SIK1

2

0

High-throughput

0.316

High

1065831

ZN844
Zinc finger protein 844

2

0

High-throughput

0.316

High

1131174

ZN827
Zinc finger protein 827

2

0

High-throughput

0.316

High

1131176

AKIR2
Akirin-2

2

0

High-throughput

0.316

High

1131180

AKND1
Protein AKNAD1

2

0

High-throughput

0.316

High

1131181

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.316

High

1131183

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

1131184

ADAL
N6-Methyl-AMP deaminase

2

0

High-throughput

0.316

High

1131185

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.316

High

1131186

PMF1
Polyamine-modulated factor 1

2

0

High-throughput

0.316

High

1131189

ZN493
Zinc finger protein 493

2

0

High-throughput

0.316

High

1131191

GOGA7
Golgin subfamily A member 7

2

0

High-throughput

0.316

High

1131193

CATAC
Centrosomal AT-AC splicing factor

2

0

High-throughput

0.316

High

1131194

CDR2L
Cerebellar degeneration-related protein 2-like

2

0

High-throughput

0.316

High

1131196

TEKL1
Tektin-like protein 1

2

0

High-throughput

0.316

High

1131197

TRM2A
tRNA

2

0

High-throughput

0.316

High

1131199

ACBD7
Acyl-CoA-binding domain-containing protein 7

2

0

High-throughput

0.316

High

1131201

FA13C
Protein FAM13C

2

0

High-throughput

0.316

High

1131207

CNOT9
CCR4-NOT transcription complex subunit 9

2

0

High-throughput

0.316

High

1131209

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

1131210

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

2

0

High-throughput

0.316

High

1131212

GTPB3
5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial

2

0

High-throughput

0.316

High

1131215

CHCH1
Small ribosomal subunit protein mS37

2

0

High-throughput

0.316

High

1131217

BORC8
BLOC-1-related complex subunit 8

2

0

High-throughput

0.316

High

1131218

COX14
Cytochrome c oxidase assembly protein COX14

2

0

High-throughput

0.316

High

1131221

TREX2
Three prime repair exonuclease 2

2

0

High-throughput

0.316

High

1131222

TEX12
Testis-expressed protein 12

2

0

High-throughput

0.316

High

1131226

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

0

High-throughput

0.316

High

1131229

CENPH
Centromere protein H

2

0

High-throughput

0.316

High

1131230

NRDE2
Nuclear exosome regulator NRDE2

2

0

High-throughput

0.316

High

1131232

NJMU
Protein Njmu-R1

2

0

High-throughput

0.316

High

1131233

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

2

0

High-throughput

0.316

High

1131234

CP4FB
Cytochrome P450 4F11

2

0

High-throughput

0.316

High

1131238

CUTC
Copper homeostasis protein cutC homolog

2

0

High-throughput

0.316

High

1131241

ABITM
Protein Abitram

2

0

High-throughput

0.316

High

1131242

MCM9
DNA helicase MCM9

2

0

High-throughput

0.316

High

1131244

RCOR3
REST corepressor 3

2

0

High-throughput

0.316

High

1131245

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

0

High-throughput

0.316

High

939494

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low

1131179

LY65C
Lymphocyte antigen 6 complex locus protein G5c

1

0

High-throughput

0.279

Low

1131198

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.279

Low

1131202

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.279

Low

1131223

RNF26
E3 ubiquitin-protein ligase RNF26

1

0

High-throughput

0.279

Low

1131224

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

0

High-throughput

0.279

Low

1131247

PGAP2
Acyltransferase PGAP2

1

0

High-throughput

0.279

Low

680703

CATS
Cathepsin S

1

0

High-throughput

0.269

Low

1131195

HOGA1
4-hydroxy-2-oxoglutarate aldolase, mitochondrial

1

0

High-throughput

0.269

Low

1131206

H1X
Histone H1.10

1

0

High-throughput

0.269

Low

1131237

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

0

High-throughput

0.269

Low

4758

TEX48
Testis-expressed protein 48

1

0

High-throughput

0.268

Low

167269

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.268

Low

259955

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.265

Low

700635

PSA5
Proteasome subunit alpha type-5

1

0

High-throughput

0.265

Low

829211

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.265

Low

1131172

IMB1
Importin subunit beta-1

1

0

High-throughput

0.265

Low

1034711

MEF2B
Myocyte-specific enhancer factor 2B

1

0

High-throughput

0.251

Low

1131251

KLH20
Kelch-like protein 20

1

0

Small-scale

0.251

Low

559956

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.249

Low

942616

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

982436

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1131175

TECT1
Tectonic-1

1

0

High-throughput

0.249

Low

1131190

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1131208

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

1131225

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025