HitPredict

Interactor 1: SAP18 (O00422)
Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)
Gene: SAP18

Interactor 2: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	39522233
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~SAP18
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 153 Hs			1 164
+	Hs
		134755 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRSF7_HUMAN (9-106): 1.03e-30: 112: 67.35
+	Hs
		134698 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65
+	Hs
		134714 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRSF5_HUMAN (10-112): 2.1e-24: 97: 44.34
+	Hs
		134499 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRS10_HUMAN (1-164): 2.26e-24: 96.6: 32.54
+	Hs
		134716 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		PABP4_HUMAN (5-91): 1.48e-21: 91.9: 26.09
+	Hs
		134542 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		PABP1_HUMAN (1-91): 1.19e-20: 89.6: 25.77
+	Hs
		134713 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRSF9_HUMAN (9-82): 1.92e-19: 83.2: 40.79
+	Hs
		134699 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRSF4_HUMAN (11-112): 3.44e-16: 76.6: 39.22
+	Hs
		134715 SAP18_HUMAN (1-153): 2.05e-90: 261: 100.00		SRSF6_HUMAN (11-88): 3.88e-16: 75.8: 47.44