HitPredict

Interactor 1: ASF1B (Q9NVP2)
Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II)
Gene: ASF1B

Interactor 2: TLK1 (Q9UKI8)
Serine/threonine-protein kinase tousled-like 1 (EC 2.7.11.1) (PKU-beta) (Tousled-like kinase 1)
Gene: TLK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.701

Property	Details
Experiments	11470414, 28514442, 17353931, 33961781
Identification Methods	enzymatic study, two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 202 Hs			1 766
+	Hs
		1356455 ASF1A_HUMAN (1-202): 2.03e-119: 338: 70.59		TLK1_HUMAN (1-766): 0: 591: 100.00
+	Hs
		1199538 ASF1B_HUMAN (1-202): 1.09e-125: 354: 100.00		TLK2_HUMAN (49-747): 9.22e-150: 458: 70.65
+	Hs
		1199551 ASF1A_HUMAN (1-202): 2.03e-119: 338: 70.59		TLK2_HUMAN (49-747): 9.22e-150: 458: 70.65
+	Ce
		711312 ASF1_CAEEL (2-166): 4.31e-88: 261: 47.27		TLK1_CAEEL (91-736): 3.89e-132: 417: 42.84
+	At
		1107513 ASF1B_ARATH (1-159): 2e-88: 260: 57.86		TSL_ARATH (41-734): 3.66e-132: 409: 36.27
+	Dm
		1215682 ASF1_DROME (1-154): 4.02e-95: 277: 71.43		Q8IRT8_DROME (210-358): 8.33e-46: 179: 40.27
+	Sc
		605945 ASF1_YEAST (1-158): 2.55e-86: 257: 58.23		RAD53_YEAST (446-747): 5.19e-22: 103: 30.03