HitPredict

Interactor 1: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Interactor 2: RPC10 (Q9Y2Y1)
DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III 12.5 kDa subunit) (RPC12.5) (RNA polymerase III subunit C11) (HsC11p) (RPC11) (hRPC11)
Gene: POLR3K

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 33961781, 24981860, 35271311, 33674783
Identification Methods affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_POL_M_15KD~RNA_pol_Rpb2_1, RNA_pol_Rpb2_1~TFIIS_C, RNA_pol_Rpb2_6~TFIIS_C
Common GO terms GO:0001056 - RNA polymerase III activity
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1133
Hs

1 108
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Last updated: 15 Jul 2024