Protein: RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor)

Gene: RPR1B, RPRD1B
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q9NQG5

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0001111 - RNA polymerase II promoter clearance
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008284 - positive regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1299001

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

7

13

Small-scale

0.971

High

1137958

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

4

15

High-throughput

0.903

High

1343447

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

3

12

Small-scale

0.873

High

625059

RPB1
DNA-directed RNA polymerase II subunit RPB1

6

17

Small-scale

0.739

High

1221370

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

5

3

Small-scale

0.727

High

677017

RPB2
DNA-directed RNA polymerase II subunit RPB2

5

14

High-throughput

0.722

High

583593

RPB3
DNA-directed RNA polymerase II subunit RPB3

5

12

High-throughput

0.718

High

181463

RPB4
DNA-directed RNA polymerase II subunit RPB4

4

6

High-throughput

0.699

High

295564

RECQ5
ATP-dependent DNA helicase Q5

4

8

High-throughput

0.699

High

583809

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

5

High-throughput

0.699

High

738891

RPB9
DNA-directed RNA polymerase II subunit RPB9

4

8

High-throughput

0.699

High

854478

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

3

High-throughput

0.699

High

913962

RPB7
DNA-directed RNA polymerase II subunit RPB7

4

8

High-throughput

0.699

High

897635

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

4

High-throughput

0.694

High

921172

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

3

High-throughput

0.694

High

124087

SPT5H
Transcription elongation factor SPT5

3

5

High-throughput

0.667

High

331600

ACL6A
Actin-like protein 6A

3

4

High-throughput

0.667

High

1182958

SPT6H
Transcription elongation factor SPT6

3

4

High-throughput

0.667

High

1336395

GPN1
GPN-loop GTPase 1

3

6

High-throughput

0.667

High

1343472

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

3

2

High-throughput

0.667

High

638407

RBTN2
Rhombotin-2

2

3

High-throughput

0.628

High

1261498

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

1

High-throughput

0.628

High

1295907

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

1

High-throughput

0.628

High

1343470

STRAP
Serine-threonine kinase receptor-associated protein

2

3

High-throughput

0.628

High

304664

SCAF4
SR-related and CTD-associated factor 4

1

3

High-throughput

0.618

High

1150701

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

3

High-throughput

0.617

High

864994

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

4

High-throughput

0.611

High

1343466

GPN3
GPN-loop GTPase 3

3

6

High-throughput

0.609

High

155646

TNPO2
Transportin-2

2

1

High-throughput

0.606

High

446918

HXC4
Homeobox protein Hox-C4

2

1

High-throughput

0.606

High

903850

NTF2
Nuclear transport factor 2

2

1

High-throughput

0.606

High

1131052

VAX1
Ventral anterior homeobox 1

2

1

High-throughput

0.606

High

1342332

HM20A
High mobility group protein 20A

2

8

High-throughput

0.606

High

244978

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.584

High

295679

RMP
Unconventional prefoldin RPB5 interactor 1

2

2

Small-scale

0.584

High

917986

H4
Histone H4

2

3

High-throughput

0.584

High

594642

PSB1
Proteasome subunit beta type-1

2

0

High-throughput

0.580

High

942446

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

2

0

High-throughput

0.580

High

1121628

BOREA
Borealin

2

0

High-throughput

0.580

High

1332101

STEEP
STING ER exit protein

2

0

High-throughput

0.580

High

361930

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

1

High-throughput

0.574

High

1343456

ASB6
Ankyrin repeat and SOCS box protein 6

2

2

High-throughput

0.574

High

1332499

RPAP3
RNA polymerase II-associated protein 3

2

5

High-throughput

0.558

High

1343452

PDRG1
p53 and DNA damage-regulated protein 1

2

2

High-throughput

0.558

High

60645

VP37C
Vacuolar protein sorting-associated protein 37C

2

4

High-throughput

0.553

High

473927

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

2

3

High-throughput

0.552

High

776828

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.537

High

125733

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.536

High

170487

TIF1A
Transcription intermediary factor 1-alpha

1

3

High-throughput

0.536

High

446802

SNRPA
U1 small nuclear ribonucleoprotein A

1

10

High-throughput

0.536

High

448824

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.536

High

508729

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

539161

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

727049

FUS
RNA-binding protein FUS

1

11

High-throughput

0.536

High

808281

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

4

High-throughput

0.536

High

854374

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

4

High-throughput

0.536

High

911974

RUXF
Small nuclear ribonucleoprotein F

1

4

High-throughput

0.536

High

960058

HXC5
Homeobox protein Hox-C5

1

1

High-throughput

0.536

High

996911

SSRP1
FACT complex subunit SSRP1

1

8

High-throughput

0.536

High

1084636

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

High-throughput

0.536

High

1087423

H2B2E
Histone H2B type 2-E

1

8

High-throughput

0.536

High

1223727

RN168
E3 ubiquitin-protein ligase RNF168

1

2

High-throughput

0.536

High

1224900

FAM9B
Protein FAM9B

1

1

High-throughput

0.536

High

1241009

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.536

High

1244309

ARI1B
AT-rich interactive domain-containing protein 1B

1

1

High-throughput

0.536

High

1270709

REQU
Zinc finger protein ubi-d4

1

6

High-throughput

0.536

High

1306543

EPAS1
Endothelial PAS domain-containing protein 1

1

2

High-throughput

0.536

High

1331824

GSX1
GS homeobox 1

1

2

High-throughput

0.536

High

1333177

SFR19
Splicing factor, arginine/serine-rich 19

1

9

High-throughput

0.536

High

1343448

ANLN
Anillin

1

1

High-throughput

0.536

High

1343451

CENPM
Centromere protein M

1

1

High-throughput

0.536

High

1075007

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.518

High

1183311

Q7KZS0
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.515

High

414379

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.513

High

1038065

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.513

High

324061

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.489

High

422459

NFM
Neurofilament medium polypeptide

1

1

High-throughput

0.489

High

574446

RL35A
Large ribosomal subunit protein eL33

1

1

High-throughput

0.489

High

661453

S10A2
Protein S100-A2

1

4

High-throughput

0.489

High

1343467

DJC12
DnaJ homolog subfamily C member 12

1

3

High-throughput

0.489

High

1343473

WIF1
Wnt inhibitory factor 1

1

2

High-throughput

0.489

High

175790

HMGB3
High mobility group protein B3

1

5

High-throughput

0.481

High

930406

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

156070

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

17

High-throughput

0.479

High

169963

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

12

High-throughput

0.479

High

179837

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

228792

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

233645

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

241646

H2B1K
Histone H2B type 1-K

1

8

High-throughput

0.479

High

270225

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

2

High-throughput

0.479

High

295289

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

317165

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

17

High-throughput

0.479

High

347976

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.479

High

377714

GCR
Glucocorticoid receptor

1

11

High-throughput

0.479

High

402754

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

2

High-throughput

0.479

High

487783

ANDR
Androgen receptor

1

11

High-throughput

0.479

High

531283

EF2
Elongation factor 2

1

3

High-throughput

0.479

High

553801

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

570092

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

614434

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.479

High

652336

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

707761

H2B1B
Histone H2B type 1-B

1

8

High-throughput

0.479

High

721529

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

738062

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

High-throughput

0.479

High

749877

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.479

High

780158

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

836015

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.479

High

902763

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.479

High

918711

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

946318

BASP1
Brain acid soluble protein 1

1

1

High-throughput

0.479

High

967457

EWS
RNA-binding protein EWS

1

9

High-throughput

0.479

High

999123

EP300
Histone acetyltransferase p300

1

5

Small-scale

0.479

High

1036111

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1052778

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

10

Small-scale

0.479

High

1118894

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

1

High-throughput

0.479

High

1188905

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1192230

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

1236520

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1269701

ESR2
Estrogen receptor beta

1

11

High-throughput

0.479

High

1271069

SYMPK
Symplekin

1

3

High-throughput

0.479

High

1286476

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.479

High

1309593

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

1

High-throughput

0.479

High

1312298

MED10
Mediator of RNA polymerase II transcription subunit 10

1

3

High-throughput

0.479

High

1326424

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.479

High

1334025

WDR76
WD repeat-containing protein 76

1

3

High-throughput

0.479

High

1334510

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

14

High-throughput

0.479

High

1343453

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

2

High-throughput

0.479

High

1343454

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

14

High-throughput

0.479

High

1343455

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

1343457

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1343458

WWOX
WW domain-containing oxidoreductase

1

5

High-throughput

0.479

High

1343460

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

8

High-throughput

0.479

High

1343462

UXT
Protein UXT

1

2

High-throughput

0.479

High

1343463

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1343465

PFD2
Prefoldin subunit 2

1

2

High-throughput

0.479

High

1343468

FBW1A
F-box/WD repeat-containing protein 1A

1

1

High-throughput

0.479

High

1343471

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

8

High-throughput

0.479

High

1343450

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

336604

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

430345

PROF1
Profilin-1

1

0

High-throughput

0.458

High

596488

PTMS
Parathymosin

1

0

High-throughput

0.458

High

653738

CALR
Calreticulin

1

0

High-throughput

0.458

High

1025564

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

1050071

SCRIB
Protein scribble homolog

1

0

Small-scale

0.458

High

1334088

ARMT1
Damage-control phosphatase ARMT1

1

0

High-throughput

0.458

High

1335498

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

529763

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

1334540

LN28A
Protein lin-28 homolog A

1

6

High-throughput

0.445

High

1343464

GCP4
Gamma-tubulin complex component 4

1

1

High-throughput

0.439

High

531993

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.437

High

670234

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.437

High

1171846

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1298305

DAA10
Dynein axonemal assembly factor 10

1

2

High-throughput

0.437

High

1331370

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1343461

PHRF1
PHD and RING finger domain-containing protein 1

1

10

High-throughput

0.437

High

1314156

Q9BVR6
Gamma-tubulin complex component

1

1

High-throughput

0.417

High

473884

MYZAP
Myocardial zonula adherens protein

1

3

High-throughput

0.407

High

1296689

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

1343469

KLH20
Kelch-like protein 20

2

0

High-throughput

0.328

High

1235164

S2541
Mitochondrial carrier protein SCaMC-3L

2

0

High-throughput

0.318

High

171680

PFD6
Prefoldin subunit 6

2

0

High-throughput

0.316

High

1203198

RASF3
Ras association domain-containing protein 3

2

0

High-throughput

0.316

High

1287670

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1343449

BIN3
Bridging integrator 3

2

0

High-throughput

0.316

High

1343459

SPG21
Maspardin

2

0

High-throughput

0.316

High

259979

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

0

High-throughput

0.279

Low

320112

CXL14
C-X-C motif chemokine 14

1

0

High-throughput

0.279

Low

444938

ANXA5
Annexin A5

1

0

High-throughput

0.279

Low

1134948

SYT6
Synaptotagmin-6

1

0

High-throughput

0.279

Low

1309436

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

149326

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

562958

STMN1
Stathmin

1

0

High-throughput

0.249

Low

897829

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.249

Low

1300752

OR4K3
Olfactory receptor 4K3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024