HitPredict

Interactor 1: CCL22 (O00626)
C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)]
Gene: CCL22

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12820969
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0071347 - cellular response to interleukin-1 GO:0071356 - cellular response to tumor necrosis factor
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 93 Hs			1 551
+	Hs
		526567 CCL4_HUMAN (3-92): 2.18e-31: 107: 33.33		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		978774 CCL14_HUMAN (8-93): 1.46e-29: 102: 26.74		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		943970 X3CL1_HUMAN (5-93): 2.04e-26: 101: 20.23		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		528260 CCL5_HUMAN (16-92): 1.1e-25: 92.7: 29.87		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		528216 CCL2_HUMAN (21-93): 2.67e-24: 89.7: 25.68		TF65_HUMAN (1-551): 0: 601: 100.00
+	Mm
		486360 CCL2_MOUSE (3-93): 5.06e-30: 105: 27.17		TF65_MOUSE (1-551): 0: 577: 87.88
+	Mm
		677067 CCL5_MOUSE (3-92): 5.79e-30: 103: 31.11		TF65_MOUSE (1-551): 0: 577: 87.88
+	Mm
		292678 CCL20_MOUSE (2-92): 9.66e-21: 80.4: 30.11		TF65_MOUSE (1-551): 0: 577: 87.88
+	Mm
		486356 CCL2_MOUSE (3-93): 5.06e-30: 105: 27.17		NFKB1_MOUSE (7-451): 3.1e-157: 475: 30.19
+	Mm
		638438 CCL5_MOUSE (3-92): 5.79e-30: 103: 31.11		NFKB1_MOUSE (7-451): 3.1e-157: 475: 30.19
+	Hs
		528261 CCL5_HUMAN (16-92): 1.1e-25: 92.7: 29.87		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		587597 CCL14_HUMAN (8-93): 1.46e-29: 102: 26.74		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587476 CCL11_HUMAN (22-93): 1.1e-24: 90.4: 30.14		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		528199 CCL2_HUMAN (21-93): 2.67e-24: 89.7: 25.68		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		134722 CCL22_HUMAN (24-93): 1.18e-23: 87.7: 100.00		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		528259 CCL5_HUMAN (16-92): 1.1e-25: 92.7: 29.87		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		587691 CCL19_HUMAN (20-93): 1.55e-20: 80: 27.63		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		134731 CCL22_HUMAN (24-93): 1.18e-23: 87.7: 100.00		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		964508 CCL17_HUMAN (7-92): 1.5e-22: 85: 32.56		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Mm
		486364 CCL2_MOUSE (3-93): 5.06e-30: 105: 27.17		NFAT5_MOUSE (6-471): 3.35e-100: 333: 17.26