HitPredict

Interactor 1: HIF1N (Q9NWT6)
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase)
Gene: HIF1AN

Interactor 2: FEM1B (Q9UK73)
Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha)
Gene: FEM1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.831

The method score is based on:

Property Details
Experiments 26972000, 17003112
Identification Methods affinity chromatography technology, two hybrid, hydroxylase assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, hydroxylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Cupin_8
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 349
Hs

1 627
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024