HitPredict

Interactor 1: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	22904686
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 693 Hs			1 1360
+	Hs
		257718 ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1356429 PCLO_HUMAN (127-534): 1.1e-09: 64.4: 10.22		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1348533 TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00		SIK3_HUMAN (7-955): 2.19e-124: 420: 14.71
+	Hs
		847120 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		SIK3_HUMAN (7-955): 2.19e-124: 420: 14.71
+	Hs
		847056 SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81		MARK4_HUMAN (7-748): 2.35e-123: 403: 18.00