HitPredict

Interactor 1: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21888893
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 183
+	Hs
		134845 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		134876 IMA3_HUMAN (1-521): 1.57e-165: 480: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		131397 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		131416 IMA4_HUMAN (1-521): 2.77e-161: 469: 85.80		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		238666 IMA7_HUMAN (1-521): 3.56e-142: 421: 46.46		CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00
+	Hs
		800322 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		853239 IMA1_HUMAN (1-521): 1.39e-145: 430: 49.62		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		238657 IMA7_HUMAN (1-521): 3.56e-142: 421: 46.46		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	At
		1276955 IMPA1_ARATH (1-521): 3.44e-158: 462: 43.72		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		984992 IMPA1_ARATH (1-521): 3.44e-158: 462: 43.72		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		97779 IMPA2_ARATH (1-521): 1.4e-157: 461: 44.69		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		97806 IMPA2_ARATH (1-521): 1.4e-157: 461: 44.69		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		285377 IMPA4_ARATH (1-521): 2.9e-155: 455: 41.64		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		285382 IMPA4_ARATH (1-521): 2.9e-155: 455: 41.64		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		1276959 IMPA6_ARATH (1-521): 2.38e-153: 450: 43.41		LHP1_ARATH (23-116): 1.44e-23: 98: 31.58
+	At
		984993 IMPA6_ARATH (1-521): 2.38e-153: 450: 43.41		Q058P7_ARATH (23-116): 1.44e-23: 98: 31.58