Interactor 1: ARHGC (Q9NZN5)
Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)
Gene: ARHGEF12

Interactor 2: ARHGC (Q9NZN5)
Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF)
Gene: ARHGEF12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 14712228
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ, PH_16~PH_16, PH_16~RhoGEF, RGS-like~RGS-like, RhoGEF~RhoGEF
Common GO terms GO:0001664 - G protein-coupled receptor binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1544
Hs

1 1544
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024