HitPredict

Interactor 1: TMOD2 (Q9NZR1)
Tropomodulin-2 (Neuronal tropomodulin) (N-Tmod)
Gene: TMOD2

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0007015 - actin filament organization
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 1294
+	Hs
		1343904 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		657551 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		1343906 TMOD4_HUMAN (4-345): 1.16e-114: 338: 54.23		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		725044 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		1348577 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41
+	Hs
		1348581 TMOD3_HUMAN (1-351): 1.22e-126: 369: 75.85		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72
+	Hs
		657463 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		657561 TMOD1_HUMAN (3-346): 2.23e-115: 340: 59.71		MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41
+	Hs
		1349403 TMOD4_HUMAN (4-345): 1.16e-114: 338: 54.23		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72