Interactor 1: IMA3 (O00629)
Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)
Gene: KPNA4

Interactor 2: TNPO1 (Q92973)
Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP)
Gene: TNPO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT_EZ~IBB, IBB~IBN_N
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
GO:0008139 - nuclear localization sequence binding
GO:0061608 - nuclear import signal receptor activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 521
Hs

1 898
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+ Dm
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+ Sp
+ Ce
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+ Dm

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Last updated: 15 Jul 2024