HitPredict

Interactor 1: CWC15 (Q9P013)
Spliceosome-associated protein CWC15 homolog
Gene: CWC15

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 33961781, 35271311, 20176811
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cwf_Cwc_15~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
and 3 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 229
Hs

1 504
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024