HitPredict

Interactor 1: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 1186
+	Hs
		261039 H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		555690 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		170185 H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		170498 H2AW_HUMAN (1-372): 5.27e-152: 434: 100.00		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		261003 H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31		NSD3_HUMAN (3-359): 2.43e-44: 177: 14.64
+	Hs
		261033 H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		260859 H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		260921 H2AY_HUMAN (1-371): 8.19e-156: 444: 66.31		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		331860 H2A1C_HUMAN (1-126): 2.96e-64: 202: 61.24		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		331824 H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		1087066 H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		555681 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		555661 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		BAZ1A_HUMAN (5-252): 1.74e-36: 152: 14.63
+	Hs
		555434 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		555528 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		1087035 H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		555569 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		555570 H2AX_HUMAN (1-144): 1.72e-66: 208: 57.14		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93
+	Hs
		1087072 H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		1087073 H2A2C_HUMAN (1-126): 7.57e-64: 201: 61.24		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93