HitPredict

Interactor 1: HM20B (Q9P0W2)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)
Gene: HMG20B

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	12032298, 34709266, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 485
+	Hs
		1342351 HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		1349874 HM20B_HUMAN (1-317): 2.24e-73: 230: 100.00		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		1223945 HM20B_HUMAN (1-317): 2.24e-73: 230: 100.00		RCOR2_HUMAN (70-482): 4.1e-111: 340: 52.96
+	Hs
		1342341 HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		1281263 SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		1223944 HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35		RCOR2_HUMAN (70-482): 4.1e-111: 340: 52.96
+	Hs
		1312032 HM20B_HUMAN (1-317): 2.24e-73: 230: 100.00		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		1312025 HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		296145 HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		1229952 HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35		MIER1_HUMAN (37-403): 4.3e-63: 215: 16.67
+	Hs
		996650 SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		295997 SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		1229951 SOX17_HUMAN (5-197): 1.67e-30: 120: 14.72		MIER1_HUMAN (37-403): 4.3e-63: 215: 16.67
+	Hs
		1162168 SOX17_HUMAN (5-197): 1.67e-30: 120: 14.72		MDEAS_HUMAN (105-381): 6.79e-46: 173: 16.67
+	Hs
		818811 SOX9_HUMAN (4-181): 2.99e-29: 118: 17.26		MDEAS_HUMAN (105-381): 6.79e-46: 173: 16.67
+	Hs
		261591 SOX17_HUMAN (5-197): 1.67e-30: 120: 14.72		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		261453 SOX10_HUMAN (18-197): 9.55e-29: 116: 16.93		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		261483 SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		1332335 SOX17_HUMAN (5-197): 1.67e-30: 120: 14.72		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		881837 SOX10_HUMAN (18-197): 9.55e-29: 116: 16.93		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11