HitPredict

Interactor 1: TRI38 (O00635)
E3 ubiquitin-protein ligase TRIM38 (EC 2.3.2.27) (RING finger protein 15) (Tripartite motif-containing protein 38) (Zinc finger protein RoRet)
Gene: TRIM38

Interactor 2: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070936 - protein K48-linked ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 465 Hs			1 207
+	Hs
		1282350 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00
+	Hs
		1297370 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02
+	Hs
		135040 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2E2_HUMAN (1-207): 5.59e-89: 261: 85.02
+	Hs
		584923 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		584907 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		584916 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		584910 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Hs
		1336390 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01
+	Hs
		919870 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		849453 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		135045 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D4_HUMAN (61-206): 1.19e-82: 243: 63.01
+	Hs
		895921 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		135019 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D2_HUMAN (61-206): 2.03e-82: 242: 65.07
+	Hs
		135012 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D1_HUMAN (61-206): 9.93e-82: 241: 61.64
+	Hs
		851889 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Hs
		135017 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		895851 TRI58_HUMAN (1-464): 5.62e-145: 425: 39.23		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		135013 TRI38_HUMAN (1-465): 7.78e-146: 426: 100.00		UB2E1_HUMAN (35-207): 2.62e-79: 236: 87.36
+	Hs
		584918 RO52_HUMAN (1-462): 2.44e-152: 443: 41.39		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27
+	Hs
		896547 TRI39_HUMAN (7-465): 2.82e-147: 431: 37.30		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27