HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: ELAV2 (Q12926)
ELAV-like protein 2 (ELAV-like neuronal protein 1) (Hu-antigen B) (HuB) (Nervous system-specific RNA-binding protein Hel-N1)
Gene: ELAVL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 579 Hs			1 359
+	Hs
		1090312 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		ELAV2_HUMAN (1-359): 4.91e-104: 311: 100.00
+	Xl
		267311 IF23A_XENLA (1-579): 1.73e-139: 419: 77.44		ELAV2_XENLA (1-359): 3.42e-97: 295: 91.16
+	Mm
		312360 IF2B1_MOUSE (1-577): 2.83e-139: 418: 71.06		ELAV4_MOUSE (1-359): 1.06e-97: 296: 82.35
+	Hs
		686657 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		ELAV4_HUMAN (1-359): 8.41e-98: 296: 82.62
+	Hs
		1128580 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		ELAV3_HUMAN (1-359): 7.51e-93: 283: 76.02
+	Hs
		135069 IF2B3_HUMAN (1-579): 5.25e-152: 450: 100.00		RBMS1_HUMAN (37-227): 8.8e-27: 111: 36.55
+	Hs
		135223 IF2B3_HUMAN (1-579): 5.25e-152: 450: 100.00		RBMS2_HUMAN (32-217): 3e-25: 107: 36.27
+	Hs
		135199 IF2B3_HUMAN (1-579): 5.25e-152: 450: 100.00		PABP4_HUMAN (10-111): 8.95e-18: 86.7: 22.55
+	Hs
		135039 IF2B3_HUMAN (1-579): 5.25e-152: 450: 100.00		PABP1_HUMAN (10-111): 2.08e-17: 85.5: 26.47
+	Hs
		135225 IF2B3_HUMAN (1-579): 5.25e-152: 450: 100.00		ELAV1_HUMAN (24-120): 5.64e-18: 85.5: 29.90
+	Hs
		713865 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		RBMS1_HUMAN (37-227): 8.8e-27: 111: 36.55
+	Hs
		1148815 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		RBMS2_HUMAN (32-217): 3e-25: 107: 36.27
+	Mm
		1000317 IF2B3_MOUSE (1-579): 2.12e-147: 438: 96.55		ELAV1_MOUSE (24-120): 6.64e-18: 85.1: 29.90
+	Xl
		267305 IF23A_XENLA (1-579): 1.73e-139: 419: 77.44		ELV1A_XENLA (24-120): 6.99e-18: 85.5: 31.96
+	Hs
		1102118 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		PABP4_HUMAN (10-111): 8.95e-18: 86.7: 22.55
+	Hs
		1152660 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		ELAV1_HUMAN (24-120): 5.64e-18: 85.5: 29.90
+	Hs
		550500 IF2B1_HUMAN (1-579): 7.39e-139: 417: 72.02		PABP1_HUMAN (10-111): 2.08e-17: 85.5: 26.47
+	Xl
		267312 IF23A_XENLA (1-579): 1.73e-139: 419: 77.44		EPABA_XENLA (10-111): 8.87e-16: 80.5: 23.53
+	Hs
		550298 PCBP1_HUMAN (277-508): 3.87e-32: 129: 24.14		PABP1_HUMAN (10-111): 2.08e-17: 85.5: 26.47
+	Hs
		1102048 FUBP1_HUMAN (353-559): 3.07e-30: 127: 23.22		PABP4_HUMAN (10-111): 8.95e-18: 86.7: 22.55