Interactor 1: E2F3 (O00716)
Transcription factor E2F3 (E2F-3)
Gene: E2F3
Interactor 2: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31130363, 17380128, 24981860, 34591612, 8657117, 19249677, 8246996, 10779361, 22157815 |
| Identification Methods | affinity chromatography technology, coimmunoprecipitation, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | E2F_CC-MB~Rb_C |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
