HitPredict

Interactor 1: ORAI1 (Q9U6B8)
Calcium release-activated calcium channel protein 1 (Protein orai)
Gene: Orai

Interactor 2: ORAI1 (Q9U6B8)
Calcium release-activated calcium channel protein 1 (Protein orai)
Gene: Orai

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 23180775, 18820677, 30160233, 31009446
Identification Methods x-ray crystallography, pull down, cross-linking study, anti tag coimmunoprecipitation, molecular sieving, static light scattering
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Orai-1~Orai-1
Common GO terms GO:0002115 - store-operated calcium entry
GO:0005246 - calcium channel regulator activity
GO:0005262 - calcium channel activity
GO:0005886 - plasma membrane
GO:0007399 - nervous system development
and 6 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 351
Dm

1 351
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024