HitPredict

Interactor 1: EP15R (Q9UBC2)
Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R)
Gene: EPS15L1

Interactor 2: EPN1 (Q9Y6I3)
Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1)
Gene: EPN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9723620
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 576
+	Hs
		787913 EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20		EPN4_HUMAN (3-561): 1.44e-89: 290: 24.14
+	Hs
		787997 EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Hs
		787969 EPS15_HUMAN (1-862): 3.59e-115: 374: 42.20		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Mm
		1194353 ITSN1_MOUSE (2-556): 1.43e-30: 132: 13.55		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Rn
		1126747 Q5JC29_RAT (1-782): 2.53e-93: 313: 42.20		SYNJ1_RAT (246-575): 3.51e-15: 81.2: 14.67
+	Mm
		1194352 EHD1_MOUSE (12-102): 9.73e-24: 108: 29.67		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Hs
		1349324 EHD2_HUMAN (262-365): 6.81e-22: 102: 34.62		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Ce
		1308345 Q9U2T9_CAEEL (119-652): 4.86e-35: 146: 17.92		Q9BI72_CAEEL (1-477): 2.39e-73: 243: 32.72
+	Mm
		1194350 EHD2_MOUSE (262-368): 1.29e-21: 101: 34.58		EPN1_MOUSE (1-576): 1.93e-88: 286: 94.44
+	Ce
		1308343 Q9U2T9_CAEEL (119-652): 4.86e-35: 146: 17.92		Q9BI71_CAEEL (1-477): 3.43e-72: 240: 32.52
+	Hs
		1331796 EHD1_HUMAN (198-366): 4.94e-14: 77.8: 25.44		EPN1_HUMAN (1-576): 4.42e-90: 290: 100.00
+	Ce
		1259347 Q8WSP1_CAEEL (118-220): 7.82e-21: 99.8: 53.33		Q9BI72_CAEEL (1-477): 2.39e-73: 243: 32.72
+	Sc
		710409 EDE1_YEAST (9-832): 2.37e-28: 125: 10.51		ENT1_YEAST (3-228): 6.81e-62: 212: 36.73
+	Hs
		307533 ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31		EPN2_HUMAN (1-566): 6.51e-54: 195: 38.02
+	Hs
		1328941 EHD2_HUMAN (262-365): 6.81e-22: 102: 34.62		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Mm
		1265097 EHD1_MOUSE (12-102): 9.73e-24: 108: 29.67		EPN3_MOUSE (1-571): 2.38e-50: 185: 37.05
+	Mm
		1206518 EHD2_MOUSE (262-368): 1.29e-21: 101: 34.58		EPN3_MOUSE (1-571): 2.38e-50: 185: 37.05
+	Dm
		91160 E3CTP7_DROME (504-831): 1.9e-12: 73.2: 8.54		Q7KU90_DROME (1-571): 4.4e-58: 209: 31.51
+	Hs
		1328938 EHD1_HUMAN (198-366): 4.94e-14: 77.8: 25.44		EPN3_HUMAN (1-571): 3.16e-55: 199: 40.16
+	Hs
		203228 ITSN1_HUMAN (1-522): 2.39e-32: 138: 13.31		SYNJ1_HUMAN (246-573): 8.14e-20: 96.3: 14.11