HitPredict

Interactor 1: NLK (Q9UBE8)
Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)
Gene: NLK

Interactor 2: NLK (Q9UBE8)
Serine/threonine-protein kinase NLK (EC 2.7.11.24) (Nemo-like kinase) (Protein LAK1)
Gene: NLK

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 26588989, 12482967, 20194509, 23602568, 17513757, 19345186
Identification Methods enzymatic study, affinity chromatography technology, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000287 - magnesium ion binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity
GO:0005524 - ATP binding
and 19 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 527
Hs

1 527
+ At
+ At
+ At
+ At
+ Hs
+ At
+ Ce
+ At
+ At
+ Zm
+ At
+ Hs
+ Hs
+ At
+ Dm
+ At
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024