HitPredict

Interactor 1: DNM1L (O00429)
Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1)
Gene: DNM1L

Interactor 2: DNM1L (O00429)
Dynamin-1-like protein (EC 3.6.5.5) (Dnm1p/Vps1p-like protein) (DVLP) (Dynamin family member proline-rich carboxyl-terminal domain less) (Dymple) (Dynamin-like protein) (Dynamin-like protein 4) (Dynamin-like protein IV) (HdynIV) (Dynamin-related protein 1)
Gene: DNM1L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.951

The method score is based on:

Property Details
Experiments 31839598, 23530241, 30914652, 20850011, 21701560, 23584531
Identification Methods cross-linking study, pull down, anti tag coimmunoprecipitation, molecular sieving, x-ray crystallography, cosedimentation in solution
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Dynamin_M~Dynamin_M, Dynamin_M~Dynamin_N, Dynamin_M~GED, Dynamin_N~Dynamin_N, Dynamin_N~GED, GED~GED
Common GO terms GO:0000266 - mitochondrial fission
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
and 40 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 736
Hs

1 736
+ Mm
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ At
+ At
+ At
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025