Interactor 1: REV1 (Q9UBZ9)
DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)
Gene: REV1

Interactor 2: POLI (Q9UNA4)
DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B)
Gene: POLI

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 15189446, 30886224, 19170759
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IMS~IMS, IMS~IMS_C, IMS_C~IMS_C
Common GO terms GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005654 - nucleoplasm
GO:0006260 - DNA replication
GO:0042276 - error-prone translesion synthesis
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1251
Hs

1 740
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ Sp
+ Dm
+ Sp
+ Sp

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Last updated: 15 Jul 2024