HitPredict

Interactor 1: CNOT8 (Q9UFF9)
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CAF1-like protein) (CALIFp) (CAF2) (CCR4-associated factor 8) (Caf1b)
Gene: CNOT8

Interactor 2: TNR6B (Q9UPQ9)
Trinucleotide repeat-containing gene 6B protein
Gene: TNRC6B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	21981923, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005829 - cytosol GO:0035195 - miRNA-mediated post-transcriptional gene silencing
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 292 Hs			1 1833
+	Hs
		1355898 CNOT7_HUMAN (1-282): 1.23e-174: 485: 76.24		TNR6B_HUMAN (28-1833): 0: 1086: 100.00
+	Hs
		1242678 CNOT8_HUMAN (1-292): 0: 514: 100.00		TNR6A_HUMAN (2-1833): 0: 785: 35.34
+	Hs
		1242684 CNOT7_HUMAN (1-282): 1.23e-174: 485: 76.24		TNR6A_HUMAN (2-1833): 0: 785: 35.34
+	Hs
		1336204 CNOT8_HUMAN (1-292): 0: 514: 100.00		TNR6C_HUMAN (34-1830): 0: 655: 34.21
+	Hs
		1336207 CNOT7_HUMAN (1-282): 1.23e-174: 485: 76.24		TNR6C_HUMAN (34-1830): 0: 655: 34.21
+	Dm
		90733 E1JHY7_DROME (2-244): 4.95e-145: 413: 69.39		GAWKY_DROME (615-1735): 3.49e-145: 488: 21.36