HitPredict

Interactor 1: D3ZCV0 (D3ZCV0)
Actinin alpha 2
Gene: Actn2

Interactor 2: NEB2 (O35274)
Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)
Gene: Ppp1r9b

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20124353
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030175 - filopodium GO:0030864 - cortical actin cytoskeleton GO:0044325 - transmembrane transporter binding GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 876 Rn			1 817
+	Rn
		192529 ACTN1_RAT (1-876): 0: 701: 80.25		NEB2_RAT (1-817): 4.47e-115: 370: 100.00
+	Mm
		1163959 ACTN1_MOUSE (1-876): 0: 697: 80.02		NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90
+	Mm
		1164079 ACTN2_MOUSE (1-876): 0: 675: 98.97		NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90
+	Hs
		725691 ACTN2_HUMAN (1-876): 0: 674: 98.17		NEB2_HUMAN (1-817): 1.43e-108: 353: 94.74
+	Mm
		885082 ACTN4_MOUSE (1-876): 0: 654: 77.53		NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90
+	Hs
		211646 ACTN4_HUMAN (1-876): 0: 658: 77.75		NEB2_HUMAN (1-817): 1.43e-108: 353: 94.74
+	Mm
		49891 A1BN54_MOUSE (1-876): 0: 699: 80.94		DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76
+	Hs
		725643 ACTN2_HUMAN (1-876): 0: 674: 98.17		DLG4_HUMAN (332-780): 1.01e-51: 195: 14.76
+	Hs
		521600 ACTN1_HUMAN (1-876): 0: 699: 80.25		ERBIN_HUMAN (14-583): 2.28e-42: 169: 13.46
+	Mm
		885081 ACTN4_MOUSE (1-876): 0: 654: 77.53		DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76
+	Hs
		725690 ACTN2_HUMAN (1-876): 0: 674: 98.17		ERBIN_HUMAN (14-583): 2.28e-42: 169: 13.46
+	Hs
		725649 ACTN2_HUMAN (1-876): 0: 674: 98.17		DLG1_HUMAN (43-803): 4.57e-35: 145: 10.10
+	Hs
		521598 ACTN1_HUMAN (1-876): 0: 699: 80.25		MAGI1_HUMAN (434-686): 2.75e-11: 69.7: 11.37
+	Hs
		211645 ACTN4_HUMAN (1-876): 0: 658: 77.75		MAGI1_HUMAN (434-686): 2.75e-11: 69.7: 11.37
+	Dm
		1182586 Q7KV70_DROME (21-533): 6.43e-102: 351: 40.45		PATJ_DROME (442-593): 2.71e-25: 114: 32.72
+	Mm
		1148440 Q68FG2_MOUSE (223-748): 9.79e-18: 90.9: 15.72		NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90
+	Mm
		1112494 Q3UGX2_MOUSE (209-751): 1.61e-16: 87: 11.36		NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90
+	Mm
		1143324 SPTB2_MOUSE (184-759): 5.23e-13: 75.4: 11.57		DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76
+	Ce
		105581 Q9XVU8_CAEEL (131-875): 6.06e-17: 87.8: 13.41		DLG1_CAEEL (358-710): 3.24e-20: 98.5: 14.17
+	Ce
		105571 Q23158_CAEEL (368-875): 1.02e-16: 87.4: 14.34		DLG1_CAEEL (358-710): 3.24e-20: 98.5: 14.17