Interactor 1: LTOR3 (Q9UHA4)
Ragulator complex protein LAMTOR3 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3) (MEK-binding partner 1) (Mp1) (Mitogen-activated protein kinase kinase 1-interacting protein 1) (Mitogen-activated protein kinase scaffold protein 1)
Gene: LAMTOR3

Interactor 2: LTOR2 (Q9Y2Q5)
Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3)
Gene: LAMTOR2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 20381137, 21516116, 11266467, 35271311, 25416956, 15016825, 32296183, 20655927, 18479705, 33961781, 21988832, 22980980, unassigned1304, 25561175
Identification Methods affinity chromatography technology, two hybrid, pull down, x-ray crystallography, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MAPKK1_Int~Robl_LC7
Common GO terms GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0008104 - protein localization
GO:0010008 - endosome membrane
GO:0031902 - late endosome membrane
and 10 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 124
Hs

1 125
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024