Protein: EMC6
ER membrane protein complex subunit 6 (Transmembrane protein 93)

Gene: EMC6
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q9BV81

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1326892

EMC5
ER membrane protein complex subunit 5

6

0

Small-scale

0.897

High

1415013

EMC3
ER membrane protein complex subunit 3

3

0

High-throughput

0.787

High

1136344

EMC2
ER membrane protein complex subunit 2

5

0

Small-scale

0.686

High

1415008

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

3

1

High-throughput

0.662

High

215644

EMC8
ER membrane protein complex subunit 8

2

1

High-throughput

0.628

High

1415016

EMC9
ER membrane protein complex subunit 9

2

1

High-throughput

0.628

High

1400538

TM237
Transmembrane protein 237

3

0

High-throughput

0.625

High

1210305

MF14B
Hippocampus abundant transcript-like protein 1

2

3

High-throughput

0.606

High

1398468

TLCD4
TLC domain-containing protein 4

2

1

High-throughput

0.606

High

1415015

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

1

High-throughput

0.606

High

1334539

RN149
E3 ubiquitin-protein ligase RNF149

2

5

Small-scale

0.584

High

722601

CTR1
High affinity cationic amino acid transporter 1

2

0

High-throughput

0.580

High

1142931

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1149880

PAQRB
Monocyte to macrophage differentiation factor

2

0

High-throughput

0.580

High

213694

AQP9
Aquaporin-9

2

8

High-throughput

0.553

High

1109034

AQP6
Aquaporin-6

2

7

High-throughput

0.553

High

1186037

SOAT
Sodium-dependent organic anion transporter

2

2

High-throughput

0.553

High

1393441

REEP6
Receptor expression-enhancing protein 6

1

1

High-throughput

0.536

High

1197275

MBRL
Membralin

1

0

High-throughput

0.513

High

1205482

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.513

High

1217114

EMC10
ER membrane protein complex subunit 10

1

0

High-throughput

0.513

High

1330378

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.513

High

1331193

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.513

High

1381336

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1382174

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1415003

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.513

High

1027167

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.489

High

230419

CREB3
Cyclic AMP-responsive element-binding protein 3

1

0

High-throughput

0.460

High

1415004

ELOV4
Very long chain fatty acid elongase 4

1

0

High-throughput

0.460

High

1249176

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1415005

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.458

High

1415010

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1131606

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.445

High

1346772

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

1

High-throughput

0.445

High

1348048

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

5

High-throughput

0.445

High

1134159

NTCP
Hepatic sodium/bile acid cotransporter

1

2

High-throughput

0.439

High

1415009

S35C2
Solute carrier family 35 member C2

1

4

High-throughput

0.439

High

218710

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

1238802

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1392453

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

380580

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

0

High-throughput

0.426

High

1365121

SL9A6
Sodium/hydrogen exchanger 6

1

0

High-throughput

0.426

High

549877

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

0

High-throughput

0.316

High

590339

MUC1
Mucin-1

2

0

High-throughput

0.316

High

1094869

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1207604

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1415007

S39A2
Zinc transporter ZIP2

2

0

High-throughput

0.316

High

1415011

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

349552

TSN15
Tetraspanin-15

1

0

High-throughput

0.279

Low

1206606

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.279

Low

1233244

NADE
Glutamine-dependent NAD(+) synthetase

1

0

High-throughput

0.279

Low

1366208

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.279

Low

1415006

GLP3L
Golgi phosphoprotein 3-like

1

0

High-throughput

0.279

Low

194743

FFAR2
Free fatty acid receptor 2

1

0

High-throughput

0.251

Low

947270

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

1005046

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1096200

TADBP
TAR DNA-binding protein 43

1

0

Small-scale

0.249

Low

1367164

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1415012

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1415017

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

1415014

FBX2
F-box only protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025