Interactor 1: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AA_permease~AA_permease, AA_permease~SLC12, SLC12~SLC12
Common GO terms GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0006884 - cell volume homeostasis
GO:0007268 - chemical synaptic transmission
GO:0008519 - ammonium channel activity
and 10 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1150
Hs

1 1085
+ Hs
+ Hs
+ Dr
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024