HitPredict

Interactor 1: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Interactor 2: FBX5 (Q9UKT4)
F-box only protein 5 (Early mitotic inhibitor 1)
Gene: FBXO5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 26496610, 35271311, 33961781, 16921029, 23708001
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle
GO:0016567 - protein ubiquitination
GO:0051301 - cell division
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 597
Hs

1 447
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Xl
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024