HitPredict

Interactor 1: CCNL1 (Q9UK58)
Cyclin-L1 (Cyclin-L)
Gene: CCNL1

Interactor 2: CD11A (Q9UQ88)
Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)
Gene: CDK11A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 14623875, 33961781, 11980906, 11683997, 23178491, 18216018
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0042981 - regulation of apoptotic process
GO:0043484 - regulation of RNA splicing
GO:0046605 - regulation of centrosome cycle
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 526
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024