Protein: SMAP2
Stromal membrane-associated protein 2 (Stromal membrane-associated protein 1-like)

Gene: SMAP2
Organism: Homo sapiens
Interactions: 187
UniProt ID: Q8WU79

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1314747

SMAP1
Stromal membrane-associated protein 1

3

7

High-throughput

0.843

High

1356350

MAGD1
Melanoma-associated antigen D1

3

1

High-throughput

0.675

High

1139092

DAZP2
DAZ-associated protein 2

4

0

High-throughput

0.670

High

574106

GLUT4
Solute carrier family 2, facilitated glucose transporter member 4

3

2

High-throughput

0.667

High

1129844

EPN4
Clathrin interactor 1

3

2

High-throughput

0.667

High

1330004

CELF5
CUGBP Elav-like family member 5

2

2

High-throughput

0.628

High

612270

ARF4
ADP-ribosylation factor 4

1

20

High-throughput

0.618

High

912795

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

10

High-throughput

0.618

High

958802

ARF3
ADP-ribosylation factor 3

1

20

High-throughput

0.618

High

1210925

CE170
Centrosomal protein of 170 kDa

1

2

High-throughput

0.618

High

1040175

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

3

1

High-throughput

0.609

High

772181

MSX2
Homeobox protein MSX-2

2

1

High-throughput

0.606

High

1047666

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.586

High

713820

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

2

3

High-throughput

0.584

High

989062

AP2B1
AP-2 complex subunit beta

2

10

High-throughput

0.584

High

155009

BHE40
Class E basic helix-loop-helix protein 40

2

0

High-throughput

0.580

High

1186672

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1356307

TET5B
Terminal nucleotidyltransferase 5B

2

0

High-throughput

0.580

High

1350959

GTR14
Solute carrier family 2, facilitated glucose transporter member 14

2

2

High-throughput

0.574

High

286396

DAB1
Disabled homolog 1

1

8

High-throughput

0.573

High

1356311

S22AC
Solute carrier family 22 member 12

2

2

High-throughput

0.567

High

210064

CRX
Cone-rod homeobox protein

2

1

High-throughput

0.553

High

347204

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

962313

RHOA
Transforming protein RhoA

1

14

High-throughput

0.536

High

1356309

STALP
AMSH-like protease

1

2

High-throughput

0.536

High

1356299

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1356331

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1350581

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.489

High

1356320

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.489

High

791569

SYUA
Alpha-synuclein

1

5

High-throughput

0.481

High

48035

RBM47
RNA-binding protein 47

1

2

High-throughput

0.479

High

91771

MCRI1
Mapk-regulated corepressor-interacting protein 1

1

1

High-throughput

0.479

High

135968

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

2

High-throughput

0.479

High

169668

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

3

High-throughput

0.479

High

171740

GAK
Cyclin-G-associated kinase

1

3

High-throughput

0.479

High

173129

XPO1
Exportin-1

1

12

High-throughput

0.479

High

175137

SC16A
Protein transport protein Sec16A

1

2

High-throughput

0.479

High

215937

SYNJ1
Synaptojanin-1

1

1

High-throughput

0.479

High

218532

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

225839

AP1G1
AP-1 complex subunit gamma-1

1

11

High-throughput

0.479

High

226149

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

242393

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

269796

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

6

High-throughput

0.479

High

269968

AUXI
Auxilin

1

2

High-throughput

0.479

High

329469

EPN2
Epsin-2

1

3

High-throughput

0.479

High

338519

SC24B
Protein transport protein Sec24B

1

1

High-throughput

0.479

High

344755

AP2A1
AP-2 complex subunit alpha-1

1

12

High-throughput

0.479

High

363618

EGFR
Epidermal growth factor receptor

1

15

High-throughput

0.479

High

483166

CLCA
Clathrin light chain A

1

3

High-throughput

0.479

High

483373

CLCB
Clathrin light chain B

1

3

High-throughput

0.479

High

541612

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

550376

PABP1
Polyadenylate-binding protein 1

1

2

High-throughput

0.479

High

610798

TCPA
T-complex protein 1 subunit alpha

1

5

High-throughput

0.479

High

641221

FGFR2
Fibroblast growth factor receptor 2

1

20

High-throughput

0.479

High

659813

SAHH
Adenosylhomocysteinase

1

2

High-throughput

0.479

High

688283

TTP
mRNA decay activator protein ZFP36

1

2

High-throughput

0.479

High

821476

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.479

High

831118

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

875729

PRC2A
Protein PRRC2A

1

4

High-throughput

0.479

High

876087

TCPE
T-complex protein 1 subunit epsilon

1

5

High-throughput

0.479

High

882062

TCPG
T-complex protein 1 subunit gamma

1

5

High-throughput

0.479

High

889314

NUMB
Protein numb homolog

1

7

High-throughput

0.479

High

899501

TCPD
T-complex protein 1 subunit delta

1

4

High-throughput

0.479

High

913891

ZN143
Zinc finger protein 143

1

1

High-throughput

0.479

High

966666

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

976447

RB11A
Ras-related protein Rab-11A

1

7

High-throughput

0.479

High

1007170

TCPB
T-complex protein 1 subunit beta

1

6

High-throughput

0.479

High

1022183

DAB2
Disabled homolog 2

1

8

High-throughput

0.479

High

1032372

OTUD4
OTU domain-containing protein 4

1

2

High-throughput

0.479

High

1049604

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1083285

AP1B1
AP-1 complex subunit beta-1

1

9

High-throughput

0.479

High

1100919

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.479

High

1107583

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

1

High-throughput

0.479

High

1107962

SQSTM
Sequestosome-1

1

7

High-throughput

0.479

High

1122115

UBP2L
Ubiquitin-associated protein 2-like

1

3

High-throughput

0.479

High

1129462

PUM1
Pumilio homolog 1

1

1

High-throughput

0.479

High

1148739

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.479

High

1149004

SC23B
Protein transport protein Sec23B

1

1

High-throughput

0.479

High

1154142

ITSN1
Intersectin-1

1

6

High-throughput

0.479

High

1165477

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

2

High-throughput

0.479

High

1213513

UBAP2
Ubiquitin-associated protein 2

1

3

High-throughput

0.479

High

1215408

TUT4
Terminal uridylyltransferase 4

1

2

High-throughput

0.479

High

1215731

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1241559

CEP85
Centrosomal protein of 85 kDa

1

2

High-throughput

0.479

High

1252347

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1254797

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1259124

LARP4
La-related protein 4

1

3

High-throughput

0.479

High

1280702

YTHD3
YTH domain-containing family protein 3

1

2

High-throughput

0.479

High

1287386

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

4

High-throughput

0.479

High

1310611

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

4

High-throughput

0.479

High

1322762

CNTRB
Centrobin

1

1

High-throughput

0.479

High

1324904

RHG18
Rho GTPase-activating protein 18

1

4

High-throughput

0.479

High

1348100

PUM2
Pumilio homolog 2

1

1

High-throughput

0.479

High

1356300

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

1

High-throughput

0.479

High

1356303

LAR4B
La-related protein 4B

1

2

High-throughput

0.479

High

1356304

CELF1
CUGBP Elav-like family member 1

1

2

High-throughput

0.479

High

1356306

DAZL
Deleted in azoospermia-like

1

2

High-throughput

0.479

High

1356312

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.479

High

1356313

ATX2
Ataxin-2

1

1

High-throughput

0.479

High

1356314

TCPH
T-complex protein 1 subunit eta

1

6

High-throughput

0.479

High

1356315

MCRI2
MAPK regulated corepressor interacting protein 2

1

1

High-throughput

0.479

High

1356317

YTHD1
YTH domain-containing family protein 1

1

2

High-throughput

0.479

High

1356318

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

1

High-throughput

0.479

High

1356319

UNK
RING finger protein unkempt homolog

1

3

High-throughput

0.479

High

1356323

ESRP2
Epithelial splicing regulatory protein 2

1

3

High-throughput

0.479

High

1356325

RC3H2
Roquin-2

1

2

High-throughput

0.479

High

1356326

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

4

High-throughput

0.479

High

1356330

BMP2K
BMP-2-inducible protein kinase

1

3

High-throughput

0.479

High

1356333

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

1356336

GGA1
ADP-ribosylation factor-binding protein GGA1

1

5

High-throughput

0.479

High

1356337

AGO2
Protein argonaute-2

1

1

High-throughput

0.479

High

1356338

AGO1
Protein argonaute-1

1

1

High-throughput

0.479

High

1356341

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

1

High-throughput

0.479

High

1356342

SMG5
Nonsense-mediated mRNA decay factor SMG5

1

1

High-throughput

0.479

High

1356344

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

1356345

RUVB1
RuvB-like 1

1

1

High-throughput

0.479

High

1356348

PRC2C
Protein PRRC2C

1

5

High-throughput

0.479

High

1356349

YTHD2
YTH domain-containing family protein 2

1

2

High-throughput

0.479

High

1356351

NUMBL
Numb-like protein

1

8

High-throughput

0.479

High

64077

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.458

High

130996

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.458

High

176524

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

181914

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.458

High

261844

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.458

High

346106

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

684325

DDX6
Probable ATP-dependent RNA helicase DDX6

1

0

High-throughput

0.458

High

963339

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.458

High

1113822

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1187053

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

1287196

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.458

High

1289175

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

1336198

RN214
RING finger protein 214

1

0

High-throughput

0.458

High

1356302

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1356305

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.458

High

1356310

FUBP3
Far upstream element-binding protein 3

1

0

High-throughput

0.458

High

1356322

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

0

High-throughput

0.458

High

1356324

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1356329

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1356334

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.458

High

1356339

SYNRG
Synergin gamma

1

0

High-throughput

0.458

High

1356347

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

537590

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.445

High

1034030

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.445

High

1199621

KLH22
Kelch-like protein 22

1

2

High-throughput

0.445

High

139943

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.437

High

189739

STX7
Syntaxin-7

1

2

High-throughput

0.437

High

390696

TFR1
Transferrin receptor protein 1

1

2

High-throughput

0.437

High

464019

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

488829

FURIN
Furin

1

2

High-throughput

0.437

High

560465

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.437

High

562264

LAMP2
Lysosome-associated membrane glycoprotein 2

1

4

High-throughput

0.437

High

630905

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.437

High

648605

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

931874

EPHA5
Ephrin type-A receptor 5

1

11

High-throughput

0.437

High

1031472

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

1034301

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.437

High

1138933

R3HD1
R3H domain-containing protein 1

1

3

High-throughput

0.437

High

1206106

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.437

High

1206500

PRC2B
Protein PRRC2B

1

4

High-throughput

0.437

High

1233382

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1242019

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.437

High

1276243

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

1293091

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1322915

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.437

High

1356328

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

2

High-throughput

0.437

High

1356332

GGA3
ADP-ribosylation factor-binding protein GGA3

1

5

High-throughput

0.437

High

1356335

GGA2
ADP-ribosylation factor-binding protein GGA2

1

4

High-throughput

0.437

High

1356340

AP4E1
AP-4 complex subunit epsilon-1

1

11

High-throughput

0.437

High

1356343

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.437

High

1356346

R3HD2
R3H domain-containing protein 2

1

4

High-throughput

0.437

High

1324741

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.426

High

255136

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

162248

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.328

High

1325878

MFD4A
Major facilitator superfamily domain-containing protein 4A

2

0

High-throughput

0.328

High

1241226

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

1356301

F168A
Protein FAM168A

1

0

High-throughput

0.299

High

231806

MFS11
UNC93-like protein MFSD11

1

0

High-throughput

0.279

Low

389452

FINC
Fibronectin

1

0

High-throughput

0.279

Low

1329163

SC5A8
Sodium-coupled monocarboxylate transporter 1

1

0

High-throughput

0.279

Low

1356308

TM45B
Transmembrane protein 45B

1

0

High-throughput

0.279

Low

50827

CA226
Uncharacterized protein C1orf226

1

0

High-throughput

0.249

Low

352500

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

619867

VCAM1
Vascular cell adhesion protein 1

1

0

High-throughput

0.249

Low

1230790

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.249

Low

1356316

DPCD
Protein DPCD

1

0

High-throughput

0.249

Low

1356327

FBSL
Fibrosin-1-like protein

1

0

High-throughput

0.249

Low

1356321

RHBG
Ammonium transporter Rh type B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025