HitPredict

Interactor 1: FBXL4 (Q9UKA2)
F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5)
Gene: FBXL4

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32877691, 36896912
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 365
+	Hs
		297112 FBXL4_HUMAN (1-621): 0: 528: 100.00		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29
+	Hs
		1230770 FXL14_HUMAN (220-541): 9.42e-32: 129: 19.89		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1222181 AMN1_HUMAN (462-615): 3.68e-20: 92.5: 19.67		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1354643 FXL17_HUMAN (181-508): 2.12e-17: 88.2: 17.20		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73189 FBXL7_HUMAN (245-586): 1.31e-36: 145: 21.55		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		1356393 FBXL2_HUMAN (121-437): 7.52e-15: 78.9: 13.78		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		1031308 SKP2_HUMAN (482-613): 1.36e-11: 69: 15.67		SGT1_HUMAN (1-365): 2.37e-88: 272: 100.00
+	Hs
		73158 FXL14_HUMAN (220-541): 9.42e-32: 129: 19.89		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		72079 B3KM70_HUMAN (121-437): 1.68e-14: 77.7: 13.78		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		73123 SKP2_HUMAN (482-613): 1.36e-11: 69: 15.67		B4DYC6_HUMAN (57-365): 4.31e-64: 207: 86.41
+	Hs
		1031262 SKP2_HUMAN (482-613): 1.36e-11: 69: 15.67		Q9BPW0_HUMAN (9-242): 3.32e-39: 147: 14.71